Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 4/20 | 0.36 |
| ▸ | CNR2 | P34972 | 4/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.32 |
| ▸ | FEN1 | P39748 | 2/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2741555 | 0.89 | CYP3A4 (0.39) | ESR2CYP3A4CYP2C9APPTGFBR1 | |
| SCHEMBL20219130 | 0.89 | CYP3A4 (0.39) | ESR2CYP3A4CYP2C9APPTGFBR1 | |
| SCHEMBL20209560 | 0.88 | CYP3A4 (0.50) | CYP3A4CYP2C9APPTGFBR1ACVR1 | |
| SCHEMBL18057052 | 0.88 | CYP3A4 (0.41) | ESR2CYP3A4CYP2C9APPTGFBR1 | |
| SCHEMBL2741558 | 0.86 | ESR2 (0.44) | ESR2CYP3A4CYP2C9APPCYP2D6 | |
| SCHEMBL20202912 | 0.86 | CYP3A4 (0.37) | CYP3A4CYP2C9APPTGFBR1ACVR1 | |
| SCHEMBL18310529 | 0.86 | FASN (0.38) | ESR2CYP3A4CYP2C9APPCYP2D6 | |
| SCHEMBL12658802 | 0.86 | TDP2 (0.45) | ESR2CYP3A4CYP2C9APPTDP2 | |
| SCHEMBL13447437 | 0.85 | ESR2 (0.42) | ESR2CYP3A4CYP2C9APPTGFBR1 | |
| SCHEMBL13636374 | 0.85 | ESR2 (0.42) | ESR2CYP3A4CYP2C9APPCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7807236-B2 | At least two liquid crystalline compounds one of which contains a 3-fluoro-4-(2,2-difluorovinyl)phenyl group; twisted or supertwisted nematic, in plane-aligned, or matrix liquid crystal displays; mobile applications | MERCK PATENT GESELLSCHAFT (DE) | 2010-10-05 | — | — | US | disclosed |
| US-20080199635-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT (DE) | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080199635-A1 | LIQUID-CRYSTALLINE MEDIUM | L1CAM, NEFM, CHRM1 | ESR2 3589/4885CYP3A4 2892/4885CYP2C9 2427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.