Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 4/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | PTPRF | P10586 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27993838 | 0.88 | PTPN5 (0.39) | PTGS2BCHEACHEPTPN5PTPN2 | |
| SCHEMBL4721556 | 0.85 | DRD2 (0.40) | PTGS2PTPN5PTPN2ALDH1A1L3MBTL1 | |
| SCHEMBL4722085 | 0.83 | DRD2 (0.41) | PTGS2PTPN5ALDH1A1HIF1AHSD17B10 | |
| SCHEMBL29266777 | 0.83 | ALDH1A1 (0.38) | PTGS2ALDH1A1HPGDHIF1AHSD17B10 | |
| SCHEMBL27849970 | 0.81 | ALDH1A1 (0.39) | PTGS2ACHEALDH1A1HPGDHIF1A | |
| SCHEMBL4723104 | 0.80 | SLC6A4 (0.41) | ACHEPTPN5ALDH1A1HPGDHIF1A | |
| SCHEMBL1311238 | 0.79 | PTGS2 (0.52) | PTGS2BCHEACHEPTPN5PTPN2 | |
| SCHEMBL4476575 | 0.79 | PTGS2 (0.56) | PTGS2BCHEACHEPTPN5PTPN2 | |
| SCHEMBL28532229 | 0.78 | HPRT1 (0.47) | PTGS2BCHEACHEALDH1A1HPGD | |
| Phosphine SCHEMBL2085257 | 0.77 | PTGS2 (0.54) | PTGS2BCHEACHEPTPN5PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461573-B2 | Organic thin film devices with stabilized threshold voltage and mobility, and method for preparing the devices | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2013-06-11 | — | — | US | disclosed |
| US-20110272674-A1 | ORGANIC THIN FILM DEVICES WITH STABILIZED THRESHOLD VOLTAGE AND MOBILITY, AND METHOD FOR PREPARING THE DEVICES | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2011-11-10 | — | — | US | disclosed |