Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 11/20 | 0.59 |
| ▸ | HTR2B | P41595 | 9/20 | 0.59 |
| ▸ | HTR2A | P28223 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11965119 | 0.84 | HTR2C (0.63) | HTR2CHTR2BHTR2AALDH1A1CYP1A2 | |
| SCHEMBL11902887 | 0.84 | HTR2C (0.63) | HTR2CHTR2BHTR2AALDH1A1CYP1A2 | |
| SCHEMBL7026793 | 0.81 | HTR2C (0.59) | HTR2CHTR2BHTR2ASLC6A4SLC6A3 | |
| SCHEMBL2829240 | 0.81 | HTR2C (0.61) | HTR2CHTR2BHTR2ASLC6A4SLC6A3 | |
| SCHEMBL2830644 | 0.81 | HTR2C (0.61) | HTR2CHTR2BHTR2ASLC6A4SLC6A3 | |
| SCHEMBL24021995 | 0.81 | HTR2C (0.65) | HTR2CHTR2BHTR2AALDH1A1CYP1A2 | |
| SCHEMBL6250305 | 0.80 | HTR2C (0.63) | HTR2CHTR2BHTR2AFFAR1MAOB | |
| SCHEMBL25262357 | 0.80 | HTR2C (0.59) | HTR2CHTR2BHTR2ACYP1A2CYP3A4 | |
| SCHEMBL17004069 | 0.78 | HTR2C (0.66) | HTR2CHTR2BHTR2AALDH1A1CYP1A2 | |
| SCHEMBL23253682 | 0.78 | CHRNB2 (0.41) | HTR2CHTR2BHTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689726-B1 | 5-(BENZ- (Z) -YLIDENE) -THIAZOLIDIN-4-ONE DERIVATIVES AS IMMUNOSUPPRESSANT AGENTS | ACTELION PHARMACEUTICALS LTD (CH) | 2010-10-06 | — | — | EP | disclosed |