Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 18/20 | 0.65 |
| ▸ | HTR2B | P41595 | 15/20 | 0.65 |
| ▸ | HTR2A | P28223 | 11/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13113993 | 0.81 | HTR2C (0.59) | HTR2CHTR2BHTR2ASLC6A4SLC6A3 | |
| SCHEMBL17004069 | 0.78 | HTR2C (0.66) | HTR2CHTR2BHTR2ASLC6A4SLC6A3 | |
| SCHEMBL11965119 | 0.76 | HTR2C (0.63) | HTR2CHTR2BHTR2ASLC6A4SLC6A3 | |
| SCHEMBL11902887 | 0.76 | HTR2C (0.63) | HTR2CHTR2BHTR2ASLC6A4SLC6A3 | |
| SCHEMBL8436378 | 0.74 | HTR2C (0.56) | HTR2CHTR2BHTR2ASLC6A4SLC6A3 | |
| SCHEMBL9382610 | 0.74 | HTR2A (0.47) | HTR2CHTR2BHTR2ASLC6A4SLC6A3 | |
| SCHEMBL13069787 | 0.73 | HTR2C (0.70) | HTR2CHTR2BHTR2ASLC6A4SLC6A3 | |
| SCHEMBL21286037 | 0.73 | HTR2C (0.47) | HTR2CHTR2BHTR2ASLC6A4SLC6A3 | |
| SCHEMBL9380158 | 0.73 | HTR2C (0.50) | HTR2CHTR2BHTR2ASLC6A4SLC6A3 | |
| SCHEMBL18906092 | 0.71 | HTR2C (0.55) | HTR2CHTR2BHTR2ASLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3524600-B1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF NOVEL SUBSTITUTED 6,7-DIHYDRO-5H-BENZO[7]ANNULENE COMPOUNDS | SANOFI SA (FR) | 2021-11-17 | — | — | EP | disclosed |