Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 13/20 | 0.63 |
| ▸ | HTR2B | P41595 | 11/20 | 0.63 |
| ▸ | HTR2A | P28223 | 8/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11965119 | 1.00 | HTR2C (0.63) | HTR2CHTR2BHTR2AALDH1A1CYP1A2 | |
| SCHEMBL13113993 | 0.84 | HTR2C (0.59) | HTR2CHTR2BHTR2AALDH1A1CYP1A2 | |
| SCHEMBL17004069 | 0.81 | HTR2C (0.66) | HTR2CHTR2BHTR2AALDH1A1CYP1A2 | |
| SCHEMBL13591154 | 0.79 | HTR2C (0.63) | HTR2CHTR2BHTR2ASLC6A4SLC6A3 | |
| SCHEMBL4893904 | 0.79 | HTR2C (0.66) | HTR2CHTR2BHTR2ASLC6A4SLC6A3 | |
| SCHEMBL2826042 | 0.79 | HTR2C (0.66) | HTR2CHTR2BHTR2ASLC6A4SLC6A3 | |
| SCHEMBL16569648 | 0.79 | HTR2C (0.41) | HTR2CHTR2BHTR2ASLC6A4SLC6A3 | |
| SCHEMBL16569276 | 0.79 | HTR2C (0.41) | HTR2CHTR2BHTR2ASLC6A4SLC6A3 | |
| SCHEMBL19262111 | 0.79 | HTR2C (0.63) | HTR2CHTR2BHTR2ASLC6A4SLC6A3 | |
| SCHEMBL16585035 | 0.79 | HTR2C (0.66) | HTR2CHTR2BHTR2ASLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120202794-A1 | COMPOUNDS | PHARMASSET, INC. (US) | 2012-08-09 | — | — | US | disclosed |
| WO-2012103113-A1 | PYRAZINE AND IMIDAZOLIDINE DERIVATIVES AND THEIR USES TO TREAT HEPATITIS C | GILEAD PHARMASSET, LLC (US) | 2012-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202794-A1 | COMPOUNDS | HAVCR2, MAVS, GOT2 | HTR2C 3437/4885HTR2B 3611/4885HTR2A 3638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.