SCHEMBL131153

SCHEMBL131153

COc1cc(N2CCOCC2)ccc1[N+]#N.COc1cc(N2CCOCC2)ccc1[N+]#N.Cl[Zn-2](Cl)(Cl)Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 6/20 0.50
▸ KMT2A Q03164 6/20 0.50
▸ THRB P10828 2/20 0.50
▸ MAPT P10636 10/20 0.45
▸ ALDH1A1 P00352 9/20 0.45
▸ HPGD P15428 4/20 0.45
▸ KDM4E B2RXH2 3/20 0.45
▸ CYP3A4 P08684 1/20 0.45
▸ TSHR P16473 1/20 0.45
▸ CYP2C19 P33261 1/20 0.45
▸ HSD17B10 Q99714 1/20 0.45
▸ POLB P06746 1/20 0.45
▸ INSR P06213 1/20 0.44
▸ ALK Q9UM73 1/20 0.44
▸ HIF1A Q16665 2/20 0.43
▸ LRRK2 Q5S007 1/20 0.43
▸ LMNA P02545 2/20 0.42
▸ NPC1 O15118 2/20 0.42
▸ RAB9A P51151 2/20 0.42
▸ HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3972410 0.95 MEN1 (0.54) MEN1KMT2ATHRBMAPTALDH1A1
Hydrochloric Acid SCHEMBL1855131 0.93 MEN1 (0.53) MEN1KMT2ATHRBMAPTALDH1A1
SCHEMBL11873266 0.92 MEN1 (0.50) MEN1KMT2ATHRBMAPTALDH1A1
Hydrochloric Acid SCHEMBL7134409 0.92 MEN1 (0.52) MEN1KMT2ATHRBMAPTALDH1A1
Hydrochloric Acid SCHEMBL7134410 0.92 MEN1 (0.52) MEN1KMT2ATHRBMAPTALDH1A1
Hydrochloric Acid SCHEMBL9304960 0.91 MEN1 (0.51) MEN1KMT2ATHRBMAPTALDH1A1
SCHEMBL10626585 0.90 MEN1 (0.50) MEN1KMT2ATHRBMAPTALDH1A1
Hydrochloric Acid SCHEMBL7794311 0.82 MEN1 (0.50) MEN1KMT2ATHRBMAPTALDH1A1
SCHEMBL28916467 0.80 MAPT (0.47) MEN1KMT2ATHRBMAPTALDH1A1
SCHEMBL10511000 0.79 SIRT6 (0.45) MEN1KMT2ATHRBMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3848708-A1 REAGENT FORMULATION FOR LEUKOCYTE TEST STRIP Roche Diagnostics GmbH (DE) 2021-07-14 — — EP claimed
US-5015572-A Colorimetric determination of active materials in body fluids for diagnosis of kidney disease, detection of leukocytes BOEHRINGER MANNHEIM GMBH (DE) 1991-05-14 — — US claimed
US-4551428-A COLORIMETRIC ANALYSIS USING DIAZONIUM COUPLERS BOEHRINGER MANNHEIM GMBH (DE) 1985-11-05 — — US claimed
JP-6086694-A — — None — — JP disclosed
EP-3848708-A1 REAGENT FORMULATION FOR LEUKOCYTE TEST STRIP Roche Diagnostics GmbH (DE) 2021-07-14 — — EP disclosed
WO-2012163361-A1 METHOD AND SYSTEM FOR IDENTIFICATION OF PHYSIOLOGICAL IMBALANCE IN AN ANIMAL AARHUS UNIVERSITET (DK) 2012-12-06 — — WO disclosed
US-8206944-B2 Dry stick device construction and method for determining an analyte in a sample using said dry stick device LATTEC I/S (DK) 2012-06-26 — — US disclosed
EP-1982182-B1 A NOVEL DRY STICK DEVICE CONSTRUCTION AND METHOD FOR DETERMINING AN ANALYTE IN A SAMPLE USING SAID DRY STICK DEVICE LATTEC I S (DK) 2012-03-07 — — EP disclosed
US-20110039290-A1 NOVEL DRY STICK DEVICE CONSTRUCTION AND METHOD FOR DETERMINING AN ANALYTE IN A SAMPLE USING SAID DRY STICK DEVICE LATTEC I/S (DK) 2011-02-17 — — US disclosed
EP-1982182-A1 A NOVEL DRY STICK DEVICE CONSTRUCTION AND METHOD FOR DETERMINING AN ANALYTE IN A SAMPLE USING SAID DRY STICK DEVICE Lattec I/S (DK) 2008-10-22 — — EP disclosed
WO-2007082544-A1 A NOVEL DRY STICK DEVICE CONSTRUCTION AND METHOD FOR DETERMINING AN ANALYTE IN A SAMPLE USING SAID DRY STICK DEVICE LATTEC I/S (DK) 2007-07-26 — — WO disclosed
JP-H0686694-A TEST PIECE FOR DETECTING ACTIVITY OF N-ACETYL-BETAD-GLUCOSAMINIDASE WAKO PURE CHEM IND LTD 1994-03-29 — — JP disclosed
US-5015572-A Colorimetric determination of active materials in body fluids for diagnosis of kidney disease, detection of leukocytes BOEHRINGER MANNHEIM GMBH (DE) 1991-05-14 — — US disclosed
US-4749648-A Agent for the determination of esterolytic and/or proteolytic enzymes BOEHRINGER MANNHEIM GMBH (DE) 1988-06-07 — — US disclosed
US-4551428-A COLORIMETRIC ANALYSIS USING DIAZONIUM COUPLERS BOEHRINGER MANNHEIM GMBH (DE) 1985-11-05 — — US disclosed
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