Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | MAPT | P10636 | 9/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | INSR | P06213 | 1/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7134409 | 0.99 | MEN1 (0.52) | MEN1KMT2ATHRBALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7134410 | 0.99 | MEN1 (0.52) | MEN1KMT2ATHRBALDH1A1MAPT | |
| SCHEMBL3972410 | 0.99 | MEN1 (0.54) | MEN1KMT2ATHRBALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL9304960 | 0.97 | MEN1 (0.51) | MEN1KMT2ATHRBALDH1A1MAPT | |
| SCHEMBL10626585 | 0.93 | MEN1 (0.50) | MEN1KMT2ATHRBALDH1A1MAPT | |
| SCHEMBL11873266 | 0.93 | MEN1 (0.50) | MEN1KMT2ATHRBALDH1A1MAPT | |
| SCHEMBL131153 | 0.93 | MEN1 (0.50) | MEN1KMT2ATHRBALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7794311 | 0.89 | MEN1 (0.50) | MEN1KMT2ATHRBALDH1A1MAPT | |
| SCHEMBL28916467 | 0.83 | MAPT (0.47) | MEN1KMT2ATHRBALDH1A1MAPT | |
| SCHEMBL10511000 | 0.82 | SIRT6 (0.45) | MEN1KMT2ATHRBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6528652-B1 | Thiazole ester and diazonium salt | CHRONIMED | 2003-03-04 | — | — | US | claimed |
| US-6503725-B2 | Compound for use in the diagnosis and treatment of urogential and kidney disorders | HYPOGUARD AMERICA LIMITED (GB) | 2003-01-07 | — | — | US | claimed |
| US-20020120151-A1 | Composition and device for detecting leukocytes in urine | HYPOGUARD AMERICA LIMITED (GB) | 2002-08-29 | — | — | US | claimed |
| US-20020058301-A1 | Composition and device for detecting leukocytes in urine | HYPOGUARD AMERICA LIMITED (GB) | 2002-05-16 | — | — | US | claimed |
| US-6348324-B1 | THIAZOLE ESTERS WHICH ARE HYDROLYZED UPON EXPOSURE TO LEUKOCYTES IN URINE AND CAN THEN REACT WITH DIAZONIUM SALTS TO PRODUCE AZO DYES | HYPOGUARD AMERICA LIMITED (GB) | 2002-02-19 | — | — | US | claimed |
| EP-1163360-A2 | COMPOSITION AND DEVICE FOR DETECTING LEUKOCYTES IN URINE | Hypoguard America Limited (US) | 2001-12-19 | — | — | EP | claimed |
| US-6180238-B1 | PARTICULARLY SUITABLE FOR USE IN INK JET PRINTING PROCESSES. | XEROX CORPORATION | 2001-01-30 | — | — | US | claimed |
| EP-0743574-B1 | Migration imaging members | XEROX CORP (US) | 2000-12-27 | — | — | EP | claimed |
| EP-0743573-B1 | Method for obtaining image contrast migration imaging members | XEROX CORP (US) | 2000-09-06 | — | — | EP | claimed |
| WO-2000043535-A2 | COMPOSITION AND DEVICE FOR DETECTING LEUKOCYTES IN URINE | HYPOGUARD AMERICA LIMITED (US) | 2000-07-27 | — | — | WO | claimed |
| US-5663044-A | Methodology for colorimetrically determining the concentration of white blood cells in a biological fluid | BAYER CORPORATION (US) | 1997-09-02 | — | — | US | claimed |
| EP-0743573-A2 | Method for obtaining image contrast migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0743574-A2 | Migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| US-5563014-A | SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT | XEROX CORPORATION (US) | 1996-10-08 | — | — | US | claimed |
| US-5534374-A | Migration imaging members | XEROX CORPORATION (US) | 1996-07-09 | — | — | US | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |
| EP-0698600-A1 | Composition, method and test device for determining the presence of leukocyte cells, esterase or protease in a test sample | Bayer Corporation (US) | 1996-02-28 | — | — | EP | claimed |
| US-5464739-A | Urinalysis, hydrolysis of lactate ester | BAYER CORPORATION (US) | 1995-11-07 | — | — | US | claimed |
| EP-0673784-A2 | Recording sheets containing oxazole, isooxazole, oxazolidinone, oxazoline salts, morpholine, thiazole, thiazolidine, thiadiazole, and phenothiazine compounds | XEROX CORPORATION (US) | 1995-09-27 | — | — | EP | claimed |
| EP-3873394-B1 | SYSTEM FOR ANALYSIS OF BODY FLUIDS AND WOUND-ASSOCIATED BIOMOLECULES | PROGENITEC INC (US) | 2025-12-24 | — | — | EP | disclosed |
| US-20230225911-A1 | ABSORBENT ARTICLE HAVING REAGENTS FOR DETECTING MEDICAL CONDITIONS | BABY RX LLC | 2023-07-20 | — | — | US | disclosed |
| CN-113242725-B | System for analyzing body fluids and wound-related biomolecules | 普吉尼科技股份有限公司 | 2023-03-28 | — | — | CN | disclosed |
| US-11506658-B2 | System for analysis of body fluids and wound-associated biomolecules | PROGENITEC, INC. (US) | 2022-11-22 | — | — | US | disclosed |
| EP-3873394-A1 | SYSTEM FOR ANALYSIS OF BODY FLUIDS AND WOUND-ASSOCIATED BIOMOLECULES | Progenitec, Inc. (US) | 2021-09-08 | — | — | EP | disclosed |
| CN-113242725-A | System for analyzing body fluids and wound-related biomolecules | 普吉尼科技股份有限公司 | 2021-08-10 | — | — | CN | disclosed |
| WO-2020219130-A1 | SYSTEM FOR ANALYSIS OF BODY FLUIDS AND WOUND-ASSOCIATED BIOMOLECULES | PROGENITEC, INC. (US) | 2020-10-29 | — | — | WO | disclosed |
| US-20200340981-A1 | SYSTEM FOR ANALYSIS OF BODY FLUIDS AND WOUND-ASSOCIATED BIOMOLECULES | Progenitec Inc. | 2020-10-29 | — | — | US | disclosed |
| US-9895094-B2 | Lateral flow device for attachment to an absorbent article | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2018-02-20 | — | — | US | disclosed |
| US-9194807-B2 | Multi-layered devices for analyte detection | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2015-11-24 | — | — | US | disclosed |
| US-20150260658-A1 | Multi-Layered Devices for Analyte Detection | KIMBERLY CLARK CO (US) | 2015-09-17 | — | — | US | disclosed |
| US-9103796-B2 | Multi-layered devices for analyte detection | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2015-08-11 | — | — | US | disclosed |
| EP-1920067-B1 | ENZYME DETECTION TECHNIQUE | KIMBERLY CLARK CO (US) | 2015-06-03 | — | — | EP | disclosed |
| US-20150025347-A1 | Lateral Flow Device for Attachment to an Absorbent Article | KIMBERLY-CLARK WORLDWIDE, INC. | 2015-01-22 | — | — | US | disclosed |
| EP-2142101-B1 | LATERAL FLOW DEVICE FOR ATTACHMENT TO AN ABSORBENT ARTICLE | KIMBERLY CLARK CO (US) | 2014-12-31 | — | — | EP | disclosed |
| EP-2220250-B1 | MULTI-LAYERED DEVICES FOR ANALYTE DETECTION | KIMBERLY CLARK CO (US) | 2014-09-03 | — | — | EP | disclosed |
| US-8609401-B2 | Detection of proteases secreted from a pathogenic microorganisms | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2013-12-17 | — | — | US | disclosed |
| CN-101558301-B | Indicator immobilization on assay devices | KIMBERLY CLARK CO | 2013-12-11 | — | — | CN | disclosed |
| US-8043272-B2 | Collection and testing of infant urine using an absorbent article | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2011-10-25 | — | — | US | disclosed |
| US-8044257-B2 | Absorbent article containing lateral flow assay device | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2011-10-25 | — | — | US | disclosed |
| US-8003399-B2 | Nitrite detection technique | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2011-08-23 | — | — | US | disclosed |
| EP-2063841-B1 | ABSORBENT ARTICLE CONTAINING LATERAL FLOW ASSAY DEVICE | KIMBERLY CLARK CO (US) | 2011-08-10 | — | — | EP | disclosed |
| US-7935538-B2 | Indicator immobilization on assay devices | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2011-05-03 | — | — | US | disclosed |
| EP-1920251-B1 | NITRITE DETECTION TECHNIQUE | KIMBERLY CLARK CO (US) | 2010-12-29 | — | — | EP | disclosed |
| WO-2010131127-A2 | ABSORBENT ARTICLES CAPABLE OF INDICATING THE PRESENCE OF URINARY TRACT INFECTIONS | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2010-11-18 | — | — | WO | disclosed |
| US-20100290948-A1 | ABSORBENT ARTICLES CAPABLE OF INDICATING THE PRESENCE OF URINARY TRACT INFECTIONS | KIMBERLY-CLARK WORLDWIDE, INC. | 2010-11-18 | — | — | US | disclosed |
| EP-2220250-A1 | MULTI-LAYERED DEVICES FOR ANALYTE DETECTION | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2010-08-25 | — | — | EP | disclosed |
| EP-2142101-A2 | LATERAL FLOW DEVICE FOR ATTACHMENT TO AN ABSORBENT ARTICLE | Kimberly-Clark Worldwide, Inc. (US) | 2010-01-13 | — | — | EP | disclosed |
| US-20090305395-A1 | Reduction of the Hook Effect in Membrane-Based Assay Devices | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2009-12-10 | — | — | US | disclosed |
| CN-101558301-A | Indicator immobilization on assay devices | KIMBERLY CLARK CO (US) | 2009-10-14 | — | — | CN | disclosed |
| EP-2092332-A1 | INDICATOR IMMOBILIZATION ON ASSAY DEVICES | Kimberly-Clark Worldwide, Inc. (US) | 2009-08-26 | — | — | EP | disclosed |
| US-7575887-B2 | Detection of proteases secreted from pathogenic microorganisms | KIMBERLY-CLARK, WORLDWIDE, INC. | 2009-08-18 | — | — | US | disclosed |
| US-20090181416-A1 | Enzyme Detection Technique | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2009-07-16 | — | — | US | disclosed |
| WO-2009077886-A1 | MULTI-LAYERED DEVICES FOR ANALYTE DETECTION | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2009-06-25 | — | — | WO | disclosed |
| US-20090155122-A1 | Multi-Layered Devices for Analyte Detection | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2009-06-18 | — | — | US | disclosed |
| EP-2063841-A1 | ABSORBENT ARTICLE CONTAINING LATERAL FLOW ASSAY DEVICE | Kimberly-Clark Worldwide, Inc. (US) | 2009-06-03 | — | — | EP | disclosed |
| US-7504235-B2 | Enzyme detection technique | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2009-03-17 | — | — | US | disclosed |
| WO-2008132619-A1 | COLLECTION AND TESTING OF INFANT URINE USING AN ABSORBENT ARTICLE | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2008-11-06 | — | — | WO | disclosed |
| WO-2008132620-A2 | LATERAL FLOW DEVICE FOR ATTACHMENT TO AN ABSORBENT ARTICLE | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2008-11-06 | — | — | WO | disclosed |
| US-20080269706-A1 | Collection and Testing of Infant Urine Using an Absorbent Article | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2008-10-30 | — | — | US | disclosed |
| US-20080269707-A1 | Lateral Flow Device for Attachment to an Absorbent Article | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2008-10-30 | — | — | US | disclosed |
| WO-2008075216-A1 | INDICATOR IMMOBILIZATION ON ASSAY DEVICES | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2008-06-26 | — | — | WO | disclosed |
| US-20080145949-A1 | Indicator immobilization on assay devices | KIMBERLY-CLARK WORLDWIDE, INC. | 2008-06-19 | — | — | US | disclosed |
| EP-1920067-A2 | ENZYME DETECTION TECHNIQUE | Kimberly-Clark Worldwide, Inc. (US) | 2008-05-14 | — | — | EP | disclosed |
| EP-1920253-A2 | DETECTION OF PROTEASES SECRETED FROM PATHOGENIC MICROORGANISMS | Kimberly-Clark Worldwide, Inc. (US) | 2008-05-14 | — | — | EP | disclosed |
| EP-1920251-A1 | NITRITE DETECTION TECHNIQUE | Kimberly-Clark Worldwide, Inc. (US) | 2008-05-14 | — | — | EP | disclosed |
| WO-2008053390-A1 | ABSORBENT ARTICLE CONTAINING LATERAL FLOW ASSAY DEVICE | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2008-05-08 | — | — | WO | disclosed |
| US-20080103414-A1 | Absorbent article containing lateral flow assay device | KIMBERLY-CLARK WORLDWIDE, INC. | 2008-05-01 | — | — | US | disclosed |
| WO-2007027198-A1 | NITRITE DETECTION TECHNIQUE | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2007-03-08 | — | — | WO | disclosed |
| WO-2007027234-A2 | ENZYME DETECTION TECHNIQUE | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2007-03-08 | — | — | WO | disclosed |
| WO-2007027353-A2 | DETECTION OF PROTEASES SECRETED FROM PATHOGENIC MICROORGANISMS | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2007-03-08 | — | — | WO | disclosed |
| US-20070048815-A1 | Enzyme detection technique | KIMBERLY-CLARK WORLDWIDE, INC. | 2007-03-01 | — | — | US | disclosed |
| US-20070048816-A1 | Detection of proteases secreted from pathogenic microorganisms | KIMBERLY-CLARK WORLDWIDE, INC. | 2007-03-01 | — | — | US | disclosed |
| US-20070048182-A1 | Nitrite detection technique | KIMBERLY-CLARK WORLDWIDE, INC. | 2007-03-01 | — | — | US | disclosed |
| EP-1156121-B1 | Urinary trypsin inhibitor assay containing a chelating agent | BAYER AG (US) | 2006-04-12 | — | — | EP | disclosed |
| US-7001737-B2 | Urinary trypsin inhibitor assay containing a chelating agent | BAYER CORPORATION (US) | 2006-02-21 | — | — | US | disclosed |
| US-6955921-B2 | Trypsin substrate and diagnostic device, and method of using same | BAYER CORPORATION (US) | 2005-10-18 | — | — | US | disclosed |
| US-6770764-B2 | DIAGNOSIS OF BACTERIA INFECTIONS | BAYER CORPORATION | 2004-08-03 | — | — | US | disclosed |
| US-20030125577-A1 | Trypsin substrate and diagnostic device, and method of using same | SIEMENS HEALTHCARE DIAGNOSTICS INC. | 2003-07-03 | — | — | US | disclosed |
| US-6528652-B1 | Thiazole ester and diazonium salt | CHRONIMED | 2003-03-04 | — | — | US | disclosed |
| US-6503725-B2 | Compound for use in the diagnosis and treatment of urogential and kidney disorders | HYPOGUARD AMERICA LIMITED (GB) | 2003-01-07 | — | — | US | disclosed |
| US-20020120151-A1 | Composition and device for detecting leukocytes in urine | HYPOGUARD AMERICA LIMITED (GB) | 2002-08-29 | — | — | US | disclosed |
| US-20020058301-A1 | Composition and device for detecting leukocytes in urine | HYPOGUARD AMERICA LIMITED (GB) | 2002-05-16 | — | — | US | disclosed |
| US-6348324-B1 | THIAZOLE ESTERS WHICH ARE HYDROLYZED UPON EXPOSURE TO LEUKOCYTES IN URINE AND CAN THEN REACT WITH DIAZONIUM SALTS TO PRODUCE AZO DYES | HYPOGUARD AMERICA LIMITED (GB) | 2002-02-19 | — | — | US | disclosed |
| US-20020004219-A1 | Trypsin substrate and diganostic device, and method of using same | SIEMENS HEALTHCARE DIAGNOSTICS INC. | 2002-01-10 | — | — | US | disclosed |
| US-20010055816-A1 | Urinary trypsin inhibitor assay containing a chelating agent | SIEMENS HEALTHCARE DIAGNOSTICS INC. | 2001-12-27 | — | — | US | disclosed |
| EP-1163360-A2 | COMPOSITION AND DEVICE FOR DETECTING LEUKOCYTES IN URINE | Hypoguard America Limited (US) | 2001-12-19 | — | — | EP | disclosed |
| EP-1157984-A2 | Trypsin substrate and diagnostic device, and method of using same | Bayer Corporation (US) | 2001-11-28 | — | — | EP | disclosed |
| EP-1156121-A2 | Urinary trypsin inhibitor assay containing a chelating agent | Bayer Corporation (US) | 2001-11-21 | — | — | EP | disclosed |
| EP-0713093-B1 | Improved methodology for colorimetrically determining the concentration of white blood cells in a biological fluid | BAYER AG (US) | 2001-10-10 | — | — | EP | disclosed |
| US-6180238-B1 | PARTICULARLY SUITABLE FOR USE IN INK JET PRINTING PROCESSES. | XEROX CORPORATION | 2001-01-30 | — | — | US | disclosed |
| EP-0743574-B1 | Migration imaging members | XEROX CORP (US) | 2000-12-27 | — | — | EP | disclosed |
| EP-0743573-B1 | Method for obtaining image contrast migration imaging members | XEROX CORP (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-2000043535-A2 | COMPOSITION AND DEVICE FOR DETECTING LEUKOCYTES IN URINE | HYPOGUARD AMERICA LIMITED (US) | 2000-07-27 | — | — | WO | disclosed |
| EP-0698600-B1 | Composition, method and test device for determining the presence of leukocyte cells, esterase or protease in a test sample | BAYER AG (US) | 1999-11-10 | — | — | EP | disclosed |
| EP-0673784-B1 | Recording sheets containing oxazole, isooxazole, oxazolidinone, oxazoline salts, morpholine, thiazole, thiazolidine, thiadiazole, and phenothiazine compounds | XEROX CORP (US) | 1999-10-27 | — | — | EP | disclosed |
| US-5729266-A | Recording sheets containing oxazole, isooxazole, oxazolidinone, oxazoline salt, morpholine, thiazole, thiazolidine, thiadiazole and phenothiazine compounds | XEROX CORPORATION (US) | 1998-03-17 | — | — | US | disclosed |
| US-5663044-A | Methodology for colorimetrically determining the concentration of white blood cells in a biological fluid | BAYER CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |
| US-5635322-A | Process for developing and overcoating migration imaging members | XEROX CORPORTION (US) | 1997-06-03 | — | — | US | disclosed |
| US-5580689-A | SOLFTENABLE LAYER OF SOFTENABLE MATERIAL, PIGMENT SENSITIVE TO INFRARED OR RED LIGHT ILLUMINATION, AND MIGRATION MARKING MATERIAL | XEROX CORPORATION (US) | 1996-12-03 | — | — | US | disclosed |
| EP-0743573-A2 | Method for obtaining image contrast migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | disclosed |
| EP-0743574-A2 | Migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | disclosed |
| US-5563014-A | SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT | XEROX CORPORATION (US) | 1996-10-08 | — | — | US | disclosed |
| US-5534374-A | Migration imaging members | XEROX CORPORATION (US) | 1996-07-09 | — | — | US | disclosed |
| EP-0713093-A2 | Improved methodology for colorimetrically determining the concentration of white blood cells in a biological fluid | Bayer Corporation (US) | 1996-05-22 | — | — | EP | disclosed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | disclosed |
| US-5512450-A | TEST PAD COMPRISING CARRIER MATRIX WITH HOMOGENEOUSLY INCORPORATED REAGENT INCLUDING HYDROXY-BLOCKED LACTATE ESTER WHICH GENERATES COMPOUND PROVIDING DETECTABLE RESPONSE WHEN HYDROLYZED, BUFFER | BAYER CORPORATION (US) | 1996-04-30 | — | — | US | disclosed |
| EP-0698600-A1 | Composition, method and test device for determining the presence of leukocyte cells, esterase or protease in a test sample | Bayer Corporation (US) | 1996-02-28 | — | — | EP | disclosed |
| US-5464739-A | Urinalysis, hydrolysis of lactate ester | BAYER CORPORATION (US) | 1995-11-07 | — | — | US | disclosed |
| EP-0673784-A2 | Recording sheets containing oxazole, isooxazole, oxazolidinone, oxazoline salts, morpholine, thiazole, thiazolidine, thiadiazole, and phenothiazine compounds | XEROX CORPORATION (US) | 1995-09-27 | — | — | EP | disclosed |
| EP-0381091-B1 | Method for the determination of an enzyme from a mixture of isoenzymes, test carrier suited for the method and its use | BOEHRINGER MANNHEIM GMBH (DE) | 1995-05-31 | — | — | EP | disclosed |
| US-5314803-A | Process and test carrier for the determination of an enzyme from an isoenzyme mixture | BOEHRINGER MANNHEIM GMBH (DE) | 1994-05-24 | — | — | US | disclosed |
| EP-0464388-A1 | Detection assays having chromogenic and nonchromogenic, hypocromogenic, bathochromogenic or hypsochromogenic substrates | TECHNICON INSTRUMENTS CORPORATION (a New York corporation) (US) | 1992-01-08 | — | — | EP | disclosed |
| EP-0154839-B1 | TEST DEVICE AND METHOD FOR THE DETECTION OF A COMPONENT OF A FLUID SAMPLE | BAYER AG (DE) | 1991-10-23 | — | — | EP | disclosed |
| US-5047324-A | Labeled Reagents In Immunometric Assays | MILES INC. (US) | 1991-09-10 | — | — | US | disclosed |
| EP-0157327-B1 | NOVEL COMPOUNDS FOR DETECTING THE PRESENCE OF HYDROLYTIC ANALYTES IN A TEST SAMPLE | MILES INC. (US) | 1991-06-12 | — | — | EP | disclosed |
| EP-0224830-B1 | GRAM NEGATIVE BACTERURIA TEST | MILES INC. (US) | 1991-01-16 | — | — | EP | disclosed |
| EP-0381091-A2 | Method for the determination of an enzyme from a mixture of isoenzymes, test carrier suited for the method and its use | Roche Diagnostics GmbH (DE) | 1990-08-08 | — | — | EP | disclosed |
| EP-0157326-B1 | COMPOSITION AND TEST DEVICE FOR DETERMINING THE PRESENCE OF LEUKOCYTES, ESTERASE AND PROTEASE IN A TEST SAMPLE | MILES INC. (US) | 1989-05-31 | — | — | EP | disclosed |
| US-4774340-A | AMINATION, CYCLIZATION, ESTERIFICATION | MILES INC. (US) | 1988-09-27 | — | — | US | disclosed |
| EP-0270930-A2 | Substantially pure enzyme-antibody conjugate preparations | MILES INC. (US) | 1988-06-15 | — | — | EP | disclosed |
| EP-0254000-A1 | Rapid detection of N. gonorrhoeae without culture | MILES INC. (US) | 1988-01-27 | — | — | EP | disclosed |
| US-4717658-A | URINARY TRACT INFECTIONS | MILES INC. (US) | 1988-01-05 | — | — | US | disclosed |
| US-4704460-A | LEUKOCYTES IN URINE | MILES LABORATORIES, INC. (US) | 1987-11-03 | — | — | US | disclosed |
| EP-0224830-A2 | Gram negative bacteruria test | MILES INC. (US) | 1987-06-10 | — | — | EP | disclosed |
| US-4657855-A | DIP-AND-READ, UROGENITAL DISORDERS | MILES LABORATORIES, INC. (US) | 1987-04-14 | — | — | US | disclosed |
| US-4645842-A | DETECTING LEUKOCYTES TO INDICATE KIDNEY OR UROGENITAL DISORDERS | MILES LABORATORIES, INC. (US) | 1987-02-24 | — | — | US | disclosed |
| EP-0157327-A2 | Novel compounds for detecting the presence of hydrolytic analytes in a test sample | MILES INC. (US) | 1985-10-09 | — | — | EP | disclosed |
| EP-0157326-A2 | Composition and test device for determining the presence of leukocytes, esterase and protease in a test sample | MILES INC. (US) | 1985-10-09 | — | — | EP | disclosed |
| EP-0154839-A2 | Test device and method for the detection of a component of a fluid sample | BAYER AG (DE) | 1985-09-18 | — | — | EP | disclosed |
| EP-0154839-A2 | Test device and method for the detection of a component of a fluid sample | BAYER AG (DE) | 1985-09-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020004219-A1 | Trypsin substrate and diganostic device, and method of using same | PRSS3, CTRL, PRSS2 | MEN1 1370/4885KMT2A 3991/4885THRB 1363/4885 |
| US-20020120151-A1 | Composition and device for detecting leukocytes in urine | CCR1, CCR3, NPPA | MEN1 3913/4885KMT2A 3183/4885THRB 204/4885 |
| US-20030125577-A1 | Trypsin substrate and diagnostic device, and method of using same | CTRL, PRSS3, SPINT2 | MEN1 796/4885KMT2A 3577/4885THRB 1101/4885 |
| US-20020058301-A1 | Composition and device for detecting leukocytes in urine | NPPA, AADAT, DNPEP | MEN1 3806/4885KMT2A 2374/4885THRB 292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.