Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | FPR3 | P25089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13806889 | 0.73 | GAA (0.41) | CYP1A2TSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL8368754 | 0.72 | ALDH1A1 (0.37) | TSHRKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL13390322 | 0.70 | RAB9A (0.45) | ALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL13117702 | 0.70 | DGAT1 (0.47) | KMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL16492277 | 0.68 | HDAC3 (0.58) | MC4RKMT2AMEN1MAPT | |
| SCHEMBL31174535 | 0.60 | GBA1 (0.48) | TSHRKMT2AMAPT | |
| SCHEMBL3861140 | 0.59 | TSHR (0.60) | MAOBCYP1A2TSHRNFKB1KMT2A | |
| SCHEMBL24803347 | 0.58 | EPHX2 (0.69) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL731620 | 0.58 | CYP1A2 (0.67) | MC4RMAOBCYP1A2TSHRNFKB1 | |
| SCHEMBL29155510 | 0.58 | ALDH1A1 (0.38) | KMT2AMEN1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010122968-A1 | DIACYLETHYLENEDIAMINE COMPOUND | アステラス製薬株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |