Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.59 |
| ▸ | RXRB | P28702 | 3/20 | 0.59 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 1/20 | 0.47 |
| ▸ | RARG | P13631 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5914350 | 0.86 | PKM (0.64) | RXRARXRBNR4A2PKMPLA2G4B | |
| SCHEMBL18607386 | 0.86 | AR (0.53) | TP53TSHRNPC1RAB9APOLB | |
| SCHEMBL5959123 | 0.86 | AR (0.53) | TP53TSHRNPC1RAB9APOLB | |
| SCHEMBL1634704 | 0.82 | PARP15 (0.58) | RXRARXRBNR4A2TSHRNPC1 | |
| SCHEMBL1635858 | 0.82 | SRD5A2 (0.65) | RXRARXRBNR4A2TP53TSHR | |
| SCHEMBL71433 | 0.82 | SRD5A2 (0.65) | RXRARXRBNR4A2TP53TSHR | |
| Terephthalic Acid SCHEMBL8989156 | 0.81 | CA1 (0.74) | RXRARXRBNR4A2MAPK1NPC1 | |
| SCHEMBL12432038 | 0.81 | MDH1 (0.45) | RXRARXRBNR4A2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL25180291 | 0.80 | SRD5A2 (0.63) | RXRARXRBNR4A2TP53TSHR | |
| Hydrochloric Acid SCHEMBL31614202 | 0.80 | SRD5A2 (0.63) | RXRARXRBNR4A2TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7812190-B2 | Derivatization and solubilization of fullerenes for use in therapeutic and diagnostic applications | TDA RESEARCH, INC. (US) | 2010-10-12 | — | — | US | disclosed |