Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 4/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 5/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12946909 | 0.89 | ALDH1A1 (0.41) | MAPK8MAPK9ALDH1A1MAPTMEN1 | |
| SCHEMBL10327120 | 0.89 | SMN1; SMN2 (0.42) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12946855 | 0.85 | NPC1 (0.40) | ALDH1A1MAPTLMNAHPGDMAPK1 | |
| SCHEMBL10327468 | 0.80 | MAPK8 (0.50) | MAPK8MAPK9ALDH1A1MAPK10PRKD3 | |
| SCHEMBL12947079 | 0.80 | MAPK8 (0.45) | MAPK8MAPK9ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL10327289 | 0.79 | MAPK8 (0.43) | MAPK8MAPK9ALDH1A1MAPTMEN1 | |
| SCHEMBL10327478 | 0.78 | ALDH1A1 (0.42) | MAPK8MAPK9ALDH1A1MAPTMEN1 | |
| SCHEMBL12946926 | 0.76 | MAPK8 (0.42) | MAPK8MAPK9MAPK10PRKD3 | |
| SCHEMBL10180692 | 0.74 | MAPK8 (0.38) | MAPK8MAPK9ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL12946841 | 0.74 | MEN1 (0.48) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816353-B2 | P70S6 kinase modulators and method of use | EXELIXIS, INC. (US) | 2010-10-19 | — | — | US | disclosed |