Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 6/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10180598 | 0.90 | MAPK8 (0.45) | MAPK8MAPK9PRKD3MAPK10 | |
| SCHEMBL10180785 | 0.87 | PIK3CD (0.37) | MAPK8MAPK9SMN1; SMN2KDM4ERXFP1 | |
| SCHEMBL10181000 | 0.85 | MEN1 (0.42) | MAPK8MAPK9SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL12946909 | 0.82 | ALDH1A1 (0.41) | MAPK8MAPK9EGFRSMN1; SMN2ALDH1A1 | |
| SCHEMBL10180844 | 0.78 | MAPK8 (0.43) | MAPK8MAPK9ALDH1A1PRKD3MAPK10 | |
| SCHEMBL10180545 | 0.76 | MAPK8 (0.41) | MAPK8MAPK9ALDH1A1PRKD3KDM4E | |
| SCHEMBL10180924 | 0.76 | MAPK8 (0.42) | MAPK8MAPK9ADORA2AADORA1PRKD3 | |
| SCHEMBL13125779 | 0.74 | MAPK8 (0.38) | MAPK8MAPK9SMN1; SMN2ALDH1A1PRKD3 | |
| SCHEMBL12947079 | 0.73 | MAPK8 (0.45) | MAPK8MAPK9EGFRSMN1; SMN2ALDH1A1 | |
| SCHEMBL10180469 | 0.72 | MEN1 (0.41) | ADORA2AADORA1SMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678168-B1 | P70S6 KINASE MODULATORS AND METHOD OF USE | EXELIXIS INC (US) | 2012-07-11 | — | — | EP | claimed |