Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12946854 | 0.85 | ALDH1A1 (0.45) | MGLLRAB9AMAPTLMNASMN1; SMN2 | |
| SCHEMBL13126328 | 0.69 | MAPT (0.50) | NPC1RAB9AMAPTLMNASMN1; SMN2 | |
| SCHEMBL13126277 | 0.68 | KMT2A (0.40) | MAPTLMNASMN1; SMN2 | |
| SCHEMBL10620437 | 0.67 | HRH4 (0.38) | MAPT | |
| SCHEMBL13125786 | 0.65 | MEN1 (0.79) | NPC1RAB9AMAPTLMNASMN1; SMN2 | |
| SCHEMBL13564689 | 0.65 | MAPT (0.46) | MAPTKDRMAPK14TNNI3K | |
| SCHEMBL27614147 | 0.65 | ALDH1A1 (0.58) | RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL13125750 | 0.65 | KMT2A (0.43) | MAPTLMNASMN1; SMN2KDRMAPK14 | |
| SCHEMBL14458281 | 0.64 | MEN1 (0.53) | MGLLNPC1RAB9AMAPTLMNA | |
| SCHEMBL12947373 | 0.64 | SMN1; SMN2 (0.44) | MGLLMAPTLMNASMN1; SMN2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816353-B2 | P70S6 kinase modulators and method of use | EXELIXIS, INC. (US) | 2010-10-19 | — | — | US | disclosed |