Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL968558 | 0.84 | LMNA (0.56) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL13126785 | 0.81 | BACE1 (0.48) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL966947 | 0.76 | BACE1 (0.47) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL13125786 | 0.75 | MEN1 (0.79) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL1007657 | 0.75 | LMNA (0.56) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL963619 | 0.75 | LMNA (0.53) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL12946806 | 0.74 | MEN1 (0.40) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL13126277 | 0.70 | KMT2A (0.40) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL13126322 | 0.69 | MGLL (0.41) | MAPTSMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL13059643 | 0.69 | MAPT (0.49) | MAPTSMN1; SMN2MEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816353-B2 | P70S6 kinase modulators and method of use | EXELIXIS, INC. (US) | 2010-10-19 | — | — | US | disclosed |