Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | NOX1 | Q9Y5S8 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYBB | P04839 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.33 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4255828 | 0.80 | MEN1 (0.38) | SNCAMEN1MAPTKMT2ANOX1 | |
| SCHEMBL1206520 | 0.71 | SNCA (0.35) | SNCAMEN1MAPTKMT2ANOX1 | |
| SCHEMBL10500347 | 0.71 | NOX1 (0.52) | SNCAMEN1MAPTKMT2ANOX1 | |
| SCHEMBL64975 | 0.71 | SNCA (0.50) | SNCAMEN1MAPTKMT2ANOX1 | |
| SCHEMBL29625245 | 0.71 | SNCA (0.50) | SNCAMEN1MAPTKMT2ANOX1 | |
| SCHEMBL29600380 | 0.71 | SNCA (0.50) | SNCAMEN1MAPTKMT2ANOX1 | |
| SCHEMBL9243182 | 0.71 | NOX1 (0.33) | SNCANOX1L3MBTL1 | |
| SCHEMBL10501378 | 0.70 | MAPT (0.47) | SNCAMEN1MAPTKMT2ANOX1 | |
| SCHEMBL31087634 | 0.70 | NOX1 (0.48) | SNCAMEN1MAPTKMT2ANOX1 | |
| SCHEMBL6247630 | 0.69 | TSHR (0.58) | GAATDP1ALDH1A1CYP19A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014200872-A9 | PHARMACEUTICAL COMPOUNDS TARGETED BY MIF AFFINITY-TETHERED MOIETIES | RJS BIOLOGICS LLC (US) | 2015-02-05 | — | — | WO | disclosed |
| WO-2014200872-A1 | PHARMACEUTICAL COMPOUNDS TARGETED BY MIF AFFINITY-TETHERED MOIETIES | RJS BIOLOGICS LLC (US) | 2014-12-18 | — | — | WO | disclosed |
| US-20130174581-A1 | SELF COOLING CONTAINER AND A COOLING DEVICE | CARLSBERG BREWERIES AlS (DK) | 2013-07-11 | — | — | US | disclosed |
| EP-2583039-A2 | A SELF COOLING CONTAINER AND A COOLING DEVICE | Carlsberg Breweries A/S (DK) | 2013-04-24 | — | — | EP | disclosed |
| WO-2011157735-A2 | A SELF COOLING CONTAINER AND A COOLING DEVICE | CARLSBERG BREWERIES A/S (DK) | 2011-12-22 | — | — | WO | disclosed |
| US-20110271692-A1 | SYSTEM AND METHOD FOR PROVIDING A SELF COOLING CONTAINER | CARLSBERG BREWERIES A/S (DK) | 2011-11-10 | — | — | US | disclosed |
| US-20110259020-A1 | SELF COOLING CONTAINER AND A COOLING DEVICE | CARLSBERG BREWERIES A/S (DK) | 2011-10-27 | — | — | US | disclosed |
| EP-2376851-A1 | A SYSTEM AND METHOD FOR PROVIDING A SELF COOLING CONTAINER | Carlsberg Breweries A/S (DK) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010066772-A1 | A SYSTEM AND METHOD FOR PROVIDING A SELF COOLING CONTAINER | CARLSBERG BREWERIES A/S (DK) | 2010-06-17 | — | — | WO | disclosed |
| EP-2196752-A1 | A self cooling container | Carlsberg Breweries A/S (DK) | 2010-06-16 | — | — | EP | disclosed |
| US-20060199243-A1 | Cytological stain composition and methods of use | PERCEPTRONIX MEDICAL INC. (CA) | 2006-09-07 | — | — | US | disclosed |