Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | NOX1 | Q9Y5S8 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | SNCA | P37840 | 2/20 | 0.38 |
| ▸ | CYBB | P04839 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.38 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1312704 | 0.80 | SNCA (0.38) | MEN1KMT2AMAPTNOX1GAA | |
| SCHEMBL30448836 | 0.76 | MAPT (0.37) | MEN1KMT2AMAPTNOX1GAA | |
| SCHEMBL31657578 | 0.76 | MAPT (0.37) | MEN1KMT2AMAPTNOX1GAA | |
| SCHEMBL20495639 | 0.76 | MAPT (0.37) | MEN1KMT2AMAPTNOX1GAA | |
| SCHEMBL1206520 | 0.74 | SNCA (0.35) | MEN1KMT2AMAPTNOX1GAA | |
| SCHEMBL29600380 | 0.74 | SNCA (0.50) | MEN1KMT2AMAPTNOX1GAA | |
| SCHEMBL29625245 | 0.74 | SNCA (0.50) | MEN1KMT2AMAPTNOX1GAA | |
| SCHEMBL64975 | 0.74 | SNCA (0.50) | MEN1KMT2AMAPTNOX1GAA | |
| SCHEMBL9243182 | 0.74 | NOX1 (0.33) | NOX1SNCAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL31175976 | 0.72 | SNCA (0.48) | MEN1KMT2AMAPTNOX1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2057136-A2 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | Wista Laboratories Ltd. (SG) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008007074-A2 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. (SG) | 2008-01-17 | — | — | WO | disclosed |