SCHEMBL1206520

SCHEMBL1206520

Nc1ccc2c(c1)Sc1cc(N)cc(I)c1N2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SNCA P37840 3/20 0.35
▸ NOX1 Q9Y5S8 5/20 0.33
▸ MEN1 O00255 4/20 0.32
▸ KMT2A Q03164 4/20 0.32
▸ L3MBTL1 Q9Y468 3/20 0.32
▸ SLC6A2 P23975 2/20 0.32
▸ HTR2C P28335 2/20 0.32
▸ ADRA2A P08913 1/20 0.32
▸ ADRA2B P18089 1/20 0.32
▸ ADRA2C P18825 1/20 0.32
▸ CHRM3 P20309 1/20 0.32
▸ SLC6A4 P31645 1/20 0.32
▸ DRD3 P35462 1/20 0.32
▸ HTR2B P41595 1/20 0.32
▸ GAA P10253 4/20 0.32
▸ MAPT P10636 4/20 0.32
▸ MAPK1 P28482 2/20 0.32
▸ NPC1 O15118 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29625245 0.80 SNCA (0.50) SNCANOX1MEN1KMT2AL3MBTL1
SCHEMBL64975 0.80 SNCA (0.50) SNCANOX1MEN1KMT2AL3MBTL1
SCHEMBL29600380 0.80 SNCA (0.50) SNCANOX1MEN1KMT2AL3MBTL1
Iodide SCHEMBL1206518 0.78 SNCA (0.48) SNCANOX1MEN1KMT2AL3MBTL1
Hydrochloric Acid SCHEMBL12470954 0.78 SNCA (0.48) SNCANOX1MEN1KMT2AL3MBTL1
Hydrochloric Acid SCHEMBL31175976 0.78 SNCA (0.48) SNCANOX1MEN1KMT2AL3MBTL1
Iodide SCHEMBL28955143 0.78 SNCA (0.48) SNCANOX1MEN1KMT2AL3MBTL1
Iodide SCHEMBL29850697 0.78 SNCA (0.48) SNCANOX1MEN1KMT2AL3MBTL1
SCHEMBL9243182 0.76 NOX1 (0.33) SNCANOX1L3MBTL1
SCHEMBL4255828 0.74 MEN1 (0.38) SNCANOX1MEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250325557-A1 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE WISTA LABORATORIES LTD. (SG) 2025-10-23 — — US disclosed
US-12324810-B2 3, 7-diamino-10H-phenothiazine salts and their use WISTA LABORATORIES LTD. (SG) 2025-06-10 — — US disclosed
US-20240245700-A1 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE WISTA LABORATORIES LTD. (SG) 2024-07-25 — — US disclosed
US-11951110-B2 3, 7-diamino-10H-phenothiazine salts and their use WISTA LABORATORIES LTD. (SG) 2024-04-09 — — US disclosed
US-11344558-B2 3, 7-diamino-10H-phenothiazine salts and their use WISTA LABORATORIES LTD. (SG) 2022-05-31 — — US disclosed
US-20220152038-A1 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE WISTA LABORATORIES LTD. (SG) 2022-05-19 — — US disclosed
US-20190151329-A1 THERAPEUTIC USE OF DIAMINOPHENOTHIAZINES WISTA LABORATORIES LTD. (SG) 2019-05-23 — — US disclosed
US-10188658-B2 Therapeutic use of diaminophenothiazines WISTA LABORATORIES LTD. (SG) 2019-01-29 — — US disclosed
US-20160051559-A1 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE WISTA LABORATORIES LTD. (SG) 2016-02-25 — — US disclosed
US-20160030444-A1 THERAPEUTIC USE OF DIAMINOPHENOTHIAZINES WISTA LABORATORIES LTD. (SG) 2016-02-04 — — US disclosed
US-8710051-B2 3,7-diamino-10H-phenothiazine salts and their use Wis Ta Laboratories Ltd. (SG) 2014-04-29 — — US disclosed
US-20110118242-A1 3,7-DIAMINO-10H-PHINOTHIAZINE SALTS AND THEIR USE WISTA LABORATORIES LTD. 2011-05-19 — — US disclosed
US-7888350-B2 3,7-diamino-10H-phenothiazine salts and their use WISTA LABORATORIES LTD. (SG) 2011-02-15 — — US disclosed
US-20100290986-A1 THERAPEUTIC USE OF DIAMINOPHENOTHIAZINES Wis Ta Laboratories Ltd. 2010-11-18 — — US disclosed
EP-2013191-B1 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE WISTA LAB LTD (SG) 2010-08-18 — — EP disclosed
EP-2205245-A1 THERAPEUTIC USE OF DIAMINOPHENOTHIAZINES Wista Laboratories Ltd. (SG) 2010-07-14 — — EP disclosed
WO-2009044127-A1 THERAPEUTIC USE OF DIAMINOPHENOTHIAZINES WISTA LABORATORIES LTD. (GB) 2009-04-09 — — WO disclosed
US-20090054419-A1 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE WISTA LABORATORIES LTD. 2009-02-26 — — US disclosed
EP-2013191-A2 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE Wista Laboratories Ltd. (SG) 2009-01-14 — — EP disclosed
WO-2007110627-A2 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE WISTA LABORATORIES LTD. (SG) 2007-10-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250325557-A1 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE PSEN1, PSEN2, APP SNCA 673/4885NOX1 187/4885MEN1 2704/4885
US-12324810-B2 3, 7-diamino-10H-phenothiazine salts and their use PSEN1, PSEN2, APP SNCA 467/4885NOX1 347/4885MEN1 3093/4885
US-20110118242-A1 3,7-DIAMINO-10H-PHINOTHIAZINE SALTS AND THEIR USE PSEN1, PSEN2, APP SNCA 1937/4885NOX1 450/4885MEN1 271/4885
US-20160051559-A1 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE PSEN1, PSEN2, APP SNCA 673/4885NOX1 187/4885MEN1 2704/4885
US-20100290986-A1 THERAPEUTIC USE OF DIAMINOPHENOTHIAZINES QDPR, DDO, HNMT SNCA 447/4885NOX1 2161/4885MEN1 370/4885
US-11951110-B2 3, 7-diamino-10H-phenothiazine salts and their use PSEN1, PSEN2, APP SNCA 673/4885NOX1 187/4885MEN1 2704/4885
US-10188658-B2 Therapeutic use of diaminophenothiazines QDPR, DDO, HNMT SNCA 430/4885NOX1 2397/4885MEN1 286/4885
US-20160030444-A1 THERAPEUTIC USE OF DIAMINOPHENOTHIAZINES QDPR, DDO, HNMT SNCA 398/4885NOX1 2264/4885MEN1 238/4885
US-11344558-B2 3, 7-diamino-10H-phenothiazine salts and their use PSEN1, PSEN2, APP SNCA 673/4885NOX1 187/4885MEN1 2704/4885
US-20220152038-A1 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE PSEN1, PSEN2, APP SNCA 437/4885NOX1 255/4885MEN1 2392/4885
US-20190151329-A1 THERAPEUTIC USE OF DIAMINOPHENOTHIAZINES QDPR, DDO, HNMT SNCA 398/4885NOX1 2264/4885MEN1 238/4885
US-20240245700-A1 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE PSEN1, PSEN2, APP SNCA 467/4885NOX1 347/4885MEN1 3093/4885
US-20090054419-A1 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE PSEN1, PSEN2, HTT SNCA 1049/4885NOX1 490/4885MEN1 327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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