Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | WNT3 | P56703 | 2/20 | 0.41 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2812403 | 0.91 | MEN1 (0.49) | MEN1KMT2ANR1H2MMP2DRD2 | |
| SCHEMBL16174305 | 0.88 | MMP2 (0.46) | NR1H2NR1H3MMP2ANPEPWNT3 | |
| SCHEMBL30638141 | 0.85 | MMP2 (0.52) | NR1H2NR1H3MMP2ANPEPCA1 | |
| SCHEMBL9507059 | 0.83 | NR1H2 (0.50) | NR1H2NR1H3MMP2WNT3SFRP1 | |
| SCHEMBL9506253 | 0.83 | NR1H2 (0.50) | NR1H2NR1H3MMP2WNT3SFRP1 | |
| SCHEMBL9503295 | 0.80 | NR1H2 (0.48) | MEN1KMT2ANR1H2NR1H3MMP2 | |
| SCHEMBL13106876 | 0.80 | NR1H2 (0.48) | MEN1KMT2ANR1H2NR1H3MMP2 | |
| SCHEMBL4502392 | 0.80 | MEN1 (0.58) | MEN1KMT2AMMP2DRD2ADRA1D | |
| SCHEMBL2011423 | 0.79 | MEN1 (0.53) | MEN1KMT2ANR1H2MMP2DRD2 | |
| SCHEMBL9006094 | 0.79 | STS (0.49) | NR1H2NR1H3MMP2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240638-A1 | Organic Compounds and their uses | NOVARTIS AG (CH) | 2010-09-23 | — | — | US | disclosed |
| US-20100240638-A1 | Organic Compounds and their uses | NOVARTIS AG (CH) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240638-A1 | Organic Compounds and their uses | OAT, HAVCR2, CYP3A43 | MEN1 4723/4885KMT2A 3834/4885NR1H2 381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.