Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | ALPL | P05186 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13128983 | 0.91 | ALDH1A1 (0.43) | ALDH1A1KMT2ASMN1; SMN2MEN1ALPL | |
| SCHEMBL2740992 | 0.78 | MEN1 (0.49) | ALDH1A1KMT2ASMN1; SMN2MEN1ALPL | |
| SCHEMBL13128922 | 0.77 | SMN1; SMN2 (0.49) | ALDH1A1KMT2ASMN1; SMN2MEN1GAA | |
| SCHEMBL8264921 | 0.70 | GAA (0.53) | ALDH1A1KMT2ASMN1; SMN2MEN1GAA | |
| SCHEMBL13128928 | 0.68 | MEN1 (0.53) | ALDH1A1KMT2ASMN1; SMN2MEN1GAA | |
| SCHEMBL13128959 | 0.66 | KDM4E (0.54) | ALDH1A1KMT2ASMN1; SMN2MEN1GAA | |
| SCHEMBL28255841 | 0.66 | GFER (0.65) | ALDH1A1KMT2ASMN1; SMN2MEN1GAA | |
| SCHEMBL13165623 | 0.66 | SMN1; SMN2 (0.43) | KMT2ASMN1; SMN2MEN1GAAMAPT | |
| SCHEMBL13586893 | 0.65 | ALDH1A1 (0.57) | ALDH1A1KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL8265977 | 0.65 | MAPT (0.67) | ALDH1A1KMT2ASMN1; SMN2MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249135-A1 | SULFONAMIDES AND THEIR USE AS A MEDICAMENT | THE GENETICS COMPANY, INC. (CH) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249135-A1 | SULFONAMIDES AND THEIR USE AS A MEDICAMENT | BCOR, CBR3, SULT1E1 | ALDH1A1 3484/4885KMT2A 217/4885SMN1; SMN2 2187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.