Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13128922 | 0.90 | SMN1; SMN2 (0.49) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2740963 | 0.90 | LMNA (0.47) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2740972 | 0.86 | MAPT (0.58) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL13128959 | 0.79 | KDM4E (0.54) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13128983 | 0.78 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL13128957 | 0.77 | L3MBTL1 (0.41) | MEN1KMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL13128956 | 0.74 | MEN1 (0.48) | MEN1KMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL2740999 | 0.72 | MAPT (0.49) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13165623 | 0.70 | SMN1; SMN2 (0.43) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL2741007 | 0.70 | MEN1 (0.58) | MEN1KMT2AALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249135-A1 | SULFONAMIDES AND THEIR USE AS A MEDICAMENT | THE GENETICS COMPANY, INC. (CH) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249135-A1 | SULFONAMIDES AND THEIR USE AS A MEDICAMENT | BCOR, CBR3, SULT1E1 | MEN1 1381/4885KMT2A 217/4885ALDH1A1 3484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.