SCHEMBL13129306

SCHEMBL13129306

O=S(=O)(Oc1cccc(-c2ccc3c4ccccc4c4ccc(-c5cccc(OS(=O)(=O)C(F)(F)F)c5)cc4c3c2)c1)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.41
ADORA2A P29274 1/20 0.40
ADORA1 P30542 1/20 0.40
DRD2 P14416 2/20 0.37
DRD1 P21728 2/20 0.37
DRD4 P21917 2/20 0.37
DRD5 P21918 2/20 0.37
DRD3 P35462 2/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC2 Q92769 1/20 0.37
KCNH2 Q12809 1/20 0.37
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA9 Q16790 2/20 0.37
PTPN5 P54829 1/20 0.36
SDHB P21912 1/20 0.36
SERPINE1 P05121 1/20 0.36
HTR1A P08908 1/20 0.36
HTR1D P28221 1/20 0.36
HTR1B P28222 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1294562 1.00 PTPN1 (0.41) PTPN1ADORA2AADORA1DRD2DRD1
SCHEMBL12715031 0.98 PTPN1 (0.40) PTPN1ADORA2AADORA1DRD2DRD1
SCHEMBL1614518 0.98 PTPN1 (0.40) PTPN1ADORA2AADORA1DRD2DRD1
SCHEMBL27818090 0.93 PTPN1 (0.43) PTPN1ADORA2AADORA1DRD2DRD3
SCHEMBL15096690 0.92 PPARG (0.41) PTPN1ADORA2AADORA1KCNH2PTPN5
SCHEMBL12487846 0.91 CA2 (0.44) PTPN1ADORA2AADORA1DRD2DRD3
SCHEMBL16211223 0.89 PDE4A (0.40) PTPN1ADORA2AADORA1HDAC1HDAC2
SCHEMBL1924438 0.88 CA2 (0.46) PTPN1ADORA2AADORA1DRD2DRD3
SCHEMBL4684800 0.87 PTPN1 (0.47) PTPN1ADORA2AADORA1DRD2DRD1
SCHEMBL13416088 0.87 CA1 (0.45) PTPN1ADORA2AADORA1DRD2DRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10374171-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-06 US disclosed
US-9997727-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-20170117489-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-04-27 US disclosed
US-9577200-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-02-21 US disclosed
EP-2185532-B1 BENZO-FUSED THIOPHENE COMPOUNDS COMPRISING A TRIPHENYLENE GROUP UNIVERSAL DISPLAY CORP (US) 2016-11-09 EP disclosed
US-20150372243-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-12-24 US disclosed
US-9153786-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-10-06 US disclosed
US-20140326977-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2014-11-06 US disclosed
US-8822708-B2 Benzo-fused thiophene / triphenylene hybrid materials UNIVERSAL DISPLAY CORPORATION (US) 2014-09-02 US disclosed
US-20130175510-A1 BENZO-FUSED THIOPHENE / TRIPHENYLENE HYBRID MATERIALS UNIVERSAL DISPLAY CORPORTION (US) 2013-07-11 US disclosed
US-8367850-B2 Benzo-fused thiophene or benzo-fused furan compounds comprising a triphenylene group UNIVERSAL DISPLAY CORPORATION (US) 2013-02-05 US disclosed
US-8367850-B2 Benzo-fused thiophene or benzo-fused furan compounds comprising a triphenylene group UNIVERSAL DISPLAY CORPORATION (US) 2013-02-05 US disclosed
US-20100237334-A1 Benzo-Fused Thiophene or Bezon-Fused Furan Compounds Comprising a Triphenylene Group UNIVERSAL DISPLAY CORPORATION (US) 2010-09-23 US disclosed
US-20100237334-A1 Benzo-Fused Thiophene or Bezon-Fused Furan Compounds Comprising a Triphenylene Group UNIVERSAL DISPLAY CORPORATION (US) 2010-09-23 US disclosed
WO-2009021126-A2 BENZO-FUSED THIOPHENE OR BENZO-FUSED FURAN COMPOUNDS COMPRISING A TRIPHENYLENE GROUP UNIVERSAL DISPLAY CORPORATION (US) 2009-02-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100237334-A1 Benzo-Fused Thiophene or Bezon-Fused Furan Compounds Comprising a Triphenylene Group TFEB, BRD4, TEC PTPN1 3966/4885ADORA2A 3856/4885ADORA1 4360/4885
US-20170117489-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TPR, EED, TEC PTPN1 4104/4885ADORA2A 2827/4885ADORA1 3870/4885
US-20150372243-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TPR, EED, TEAD2 PTPN1 4385/4885ADORA2A 4031/4885ADORA1 4673/4885
US-10374171-B2 Organic electroluminescent materials and devices TPR, EED, TEAD2 PTPN1 4385/4885ADORA2A 4031/4885ADORA1 4673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.