Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.48 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 2/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13132713 | 0.98 | MAPT (0.48) | MAPTSAE1UBA2NR1H4NPC1 | |
| SCHEMBL13132557 | 0.95 | RAB9A (0.48) | MAPTSAE1UBA2NR1H4NPC1 | |
| SCHEMBL13132544 | 0.86 | NPC1 (0.52) | MAPTNPC1RAB9ASMN1; SMN2MITF | |
| SCHEMBL13023081 | 0.80 | THRB (0.45) | MAPTSAE1UBA2NR1H4MMP2 | |
| SCHEMBL13132548 | 0.80 | NPC1 (0.50) | MAPTNPC1RAB9ASMN1; SMN2MITF | |
| SCHEMBL13132571 | 0.79 | PTPN11 (0.61) | MAPTNPC1RAB9ASMN1; SMN2MITF | |
| SCHEMBL13022965 | 0.78 | NR1H4 (0.44) | MAPTSAE1UBA2NR1H4MMP2 | |
| SCHEMBL13168717 | 0.78 | RAB9A (0.47) | MAPTNPC1RAB9ASMN1; SMN2MITF | |
| SCHEMBL13400501 | 0.77 | KCNK3 (0.46) | MAPTSAE1UBA2NR1H4ALDH1A1 | |
| SCHEMBL13132700 | 0.77 | NPC1 (0.50) | MAPTNPC1RAB9ASMN1; SMN2MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | FUJIFILM CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | NAT1, KATNA1, KAT2B | MAPT 4057/4885SAE1 419/4885UBA2 997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.