Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13132745 | 0.97 | MEN1 (0.61) | MEN1KMT2ALMNAPTPN11RAB9A | |
| SCHEMBL13169356 | 0.87 | MEN1 (0.51) | MEN1KMT2ALMNAPTPN11RAB9A | |
| SCHEMBL13132583 | 0.85 | KDM4E (0.67) | MEN1KMT2ALMNAPTPN11RAB9A | |
| SCHEMBL13023381 | 0.85 | HDAC1 (0.64) | MEN1KMT2ARAB9AMAPTPKM | |
| SCHEMBL13132582 | 0.85 | L3MBTL1 (0.73) | MEN1KMT2ATP53PKML3MBTL1 | |
| SCHEMBL30444179 | 0.84 | TSHR (0.52) | MEN1KMT2ARAB9ASMN1; SMN2TP53 | |
| SCHEMBL166803 | 0.84 | TSHR (0.52) | MEN1KMT2ARAB9ASMN1; SMN2TP53 | |
| SCHEMBL13132523 | 0.84 | RAB9A (0.54) | MEN1KMT2ALMNARAB9AMAPT | |
| SCHEMBL15907176 | 0.82 | KMT2A (0.61) | MEN1KMT2ALMNARAB9ASMN1; SMN2 | |
| SCHEMBL13132747 | 0.82 | KDM4E (0.62) | MEN1KMT2ALMNAPTPN11RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | FUJIFILM CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | NAT1, KATNA1, KAT2B | MEN1 579/4885KMT2A 730/4885LMNA 1650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.