SCHEMBL166803

SCHEMBL166803

C#Cc1cccc(C(=O)OC)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.52
LOXL2 Q9Y4K0 1/20 0.51
CYP4F2 P78329 2/20 0.50
CYP4A11 Q02928 2/20 0.50
RAB9A P51151 3/20 0.49
POLB P06746 1/20 0.49
ALDH1A1 P00352 3/20 0.47
GLRA3 O75311 1/20 0.47
GLRB P48167 1/20 0.47
NPC1 O15118 2/20 0.46
CYP3A4 P08684 2/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
MAPK1 P28482 1/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
XDH P47989 1/20 0.46
CA9 Q16790 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30444179 1.00 TSHR (0.52) TSHRLOXL2CYP4F2CYP4A11RAB9A
SCHEMBL13132575 0.84 MEN1 (0.65) RAB9AALDH1A1NPC1MEN1KMT2A
SCHEMBL13132745 0.84 MEN1 (0.61) RAB9AALDH1A1NPC1MEN1KMT2A
SCHEMBL1800821 0.84 TSHR (0.53) TSHRLOXL2CYP4F2CYP4A11RAB9A
Methyl Benzoate SCHEMBL28358400 0.84 TSHR (0.70) TSHRRAB9APOLBALDH1A1NPC1
SCHEMBL23380281 0.82 EGFR (0.55) TSHRGLRA3GLRBMEN1KMT2A
SCHEMBL10411912 0.82 ALDH1A1 (0.52) TSHRLOXL2CYP4F2CYP4A11RAB9A
SCHEMBL16618914 0.82 TSHR (0.52) TSHRLOXL2CYP4F2CYP4A11RAB9A
SCHEMBL3851983 0.82 TSHR (0.52) TSHRLOXL2CYP4F2CYP4A11RAB9A
SCHEMBL60040 0.82 MRGPRX4 (0.56) TSHRLOXL2CYP4F2CYP4A11RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120132861-A Copper-based high-entropy alloy material and preparation method and application thereof 温州大学新材料与产业技术研究院 2025-06-13 CN claimed
EP-3051946-B1 USE OF SUBSTITUTED DIHYDROOXINDOLYLSULFONAMIDES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE IN PLANTS BAYER CROPSCIENCE AG (DE) 2017-11-29 EP claimed
EP-0050428-A1 Ethynylated aromatic compounds and process for making same Hughes Aircraft Company (US) 1982-04-28 EP claimed
EP-4712967-A2 G-PROTEIN COUPLED RECEPTOR ANTAGONIST Enveda Therapeutics, Inc. (US) 2026-03-25 EP disclosed
US-12441726-B2 Compounds and uses thereof FOGHORN THERAPEUTICS, INC. (US) 2025-10-14 US disclosed
US-20250304576-A1 IKK INHIBITORS CANCER RESEARCH TECH LTD (GB) 2025-10-02 US disclosed
US-12351570-B2 Disubstituted alkyne derivatives MERCK PATENT GMBH (DE) 2025-07-08 US disclosed
CN-120132861-A Copper-based high-entropy alloy material and preparation method and application thereof 温州大学新材料与产业技术研究院 2025-06-13 CN disclosed
EP-4522597-A1 IKK INHIBITORS Cancer Research Technology Limited (GB) 2025-03-19 EP disclosed
CN-119562945-A IKK inhibitors 癌症研究技术有限公司 2025-03-04 CN disclosed
WO-2024239000-A2 G-PROTEIN COUPLED RECEPTOR ANTAGONIST ENVEDA THERAPEUTICS, INC. (US) 2024-11-21 WO disclosed
US-5624943-A Pyridine compounds which are useful as leukotriene-B4 -antagonists SCHERING AKTIENGESELLSCHAFT (DE) 1997-04-29 US disclosed
US-5614634-A Leukotriene-B4 derivatives, process for their production and their use as pharmaceutical agents SCHERING AKTIENGESELLSCHAFT (DE) 1997-03-25 US disclosed
US-5440044-A Leukotriene-B4 derivatives, process for their production and their use as pharmaceutical agents SCHERING AKTIENGESELLSCHAFT (DE) 1995-08-08 US disclosed
EP-0575494-A4 1994-04-20 EP disclosed
EP-0575494-A1 LEUKOTRIENE ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1993-12-29 EP disclosed
WO-1993022285-A1 LEUKOTRIENE ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1993-11-11 WO disclosed
WO-1992016104-A1 LEUKOTRIENE ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1992-10-01 WO disclosed
US-4465833-A ALKYNYLATION HALOGENATED BENZENE COMPOUND IN PRESENCE OF METAL CATALYST HUGHES AIRCRAFT COMPANY (US) 1984-08-14 US disclosed
EP-0050428-A1 Ethynylated aromatic compounds and process for making same Hughes Aircraft Company (US) 1982-04-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304576-A1 IKK INHIBITORS NFKBIA, IKBKE, IKBKB TSHR 3502/4885LOXL2 4478/4885CYP4F2 4484/4885
US-12351570-B2 Disubstituted alkyne derivatives BRCA1, MYC, PCNA TSHR 3500/4885LOXL2 1039/4885CYP4F2 2833/4885
US-12441726-B2 Compounds and uses thereof VHL, CLN6, TFEB TSHR 4351/4885LOXL2 2917/4885CYP4F2 2084/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.