SCHEMBL13133441

SCHEMBL13133441

C[Si](C)(C)c1ccc(N2c3ccc(Br)cc3Oc3cc(Br)ccc32)cc1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
AHR P35869 3/20 0.41
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
FAAH O00519 1/20 0.31
MGLL Q99685 1/20 0.31
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
ALOX15 P16050 1/20 0.31
ALOX12 P18054 1/20 0.31
HBB P68871 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29534796 0.86 AHR (0.50) AHRESR1ESR2FAAHMGLL
SCHEMBL23660862 0.86 AHR (0.50) AHRESR1ESR2FAAHMGLL
SCHEMBL13328077 0.83 AHR (0.44) AHRESR1ESR2MGLLMEN1
SCHEMBL12440940 0.81 AHR (0.41) AHRESR1ESR2MGLLMEN1
SCHEMBL13429672 0.80 AHR (0.33) AHR
SCHEMBL12195289 0.80 AHR (0.52) AHRMGLL
SCHEMBL13326597 0.79 MGLL (0.41) AHRMGLLMEN1MAPTKMT2A
SCHEMBL15583795 0.79 AHR (0.40) AHRESR1ESR2FAAHMGLL
SCHEMBL18545086 0.77 AHR (0.46) AHRFAAHMGLLMEN1KMT2A
SCHEMBL13125131 0.77 AHR (0.46) AHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110309341-A1 AMINE POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME SUMATION CO., LTD. (JP) 2011-12-22 US disclosed
US-20110309341-A1 AMINE POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME SUMATION CO., LTD. (JP) 2011-12-22 US disclosed
US-20100230666-A1 AMINE-TYPE POLYMERIC COMPOUND, AND LIGHT-EMITTING ELEMENT COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100230666-A1 AMINE-TYPE POLYMERIC COMPOUND, AND LIGHT-EMITTING ELEMENT COMPRISING THE SAME AHR, ARNT, MLLT1 AHR 1/4885MMP2 4852/4885MMP9 4773/4885
US-20110309341-A1 AMINE POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME AHR, HRH3, HRH4 AHR 1/4885MMP2 4795/4885MMP9 4532/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.