SCHEMBL23660862

SCHEMBL23660862

Brc1ccc(N2c3ccc(Br)cc3Oc3cc(Br)ccc32)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 6/20 0.50
FAAH O00519 1/20 0.41
MGLL Q99685 1/20 0.41
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
MAPT P10636 2/20 0.33
BLM P54132 2/20 0.33
PGR P06401 1/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
HTR7 P34969 1/20 0.33
HTR2B P41595 1/20 0.33
TMEM97 Q5BJF2 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
CYP2A6 P11509 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
ALOX15 P16050 1/20 0.32
ALOX12 P18054 1/20 0.32
HBB P68871 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29534796 1.00 AHR (0.50) AHRFAAHMGLLESR1ESR2
SCHEMBL13328077 0.89 AHR (0.44) AHRMGLLESR1ESR2MAPT
SCHEMBL12195289 0.89 AHR (0.52) AHRMGLLPGRCYP2A6
SCHEMBL13133441 0.86 AHR (0.41) AHRFAAHMGLLESR1ESR2
SCHEMBL12440940 0.86 AHR (0.41) AHRMGLLESR1ESR2MAPT
SCHEMBL28227794 0.85 ALDH1A1 (0.40) AHRFAAHMGLLMAPTPGR
SCHEMBL15583795 0.85 AHR (0.40) AHRFAAHMGLLESR1ESR2
SCHEMBL13326597 0.85 MGLL (0.41) AHRMGLLMAPTLMNAMEN1
SCHEMBL15028231 0.85 AHR (0.40) AHRFAAHMGLLPGRTP53
SCHEMBL15470432 0.84 AHR (0.52) AHRMAPTBLMPGRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112625004-B Novel photo-activated organic small molecule matrix, preparation method and application thereof in MALDI mass spectrometry detection 苏州大学 2022-10-11 CN disclosed
CN-114249902-B Preparation method and application of phenoxazine-based metal organic framework with visible light catalytic reduction C-F bond performance 大连理工大学 2022-08-26 CN disclosed
WO-2022126819-A1 PHOTOACTIVATED NOVEL ORGANIC SMALL-MOLECULAR MATRIX, PREPARATION METHOD THEREFOR AND USE THEREOF IN MALDI MASS SPECTROMETRY DETECTION 苏州大学 2022-06-23 WO disclosed
CN-114249902-A Preparation method and application of phenoxazine-based metal organic framework with visible light catalytic reduction C-F bond performance 大连理工大学 2022-03-29 CN disclosed
US-20210226129-A1 CHARGE TRANSPORT MATERIAL, INK COMPOSITION USING SAID MATERIAL, ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY ELEMENT, LIGHTING DEVICE AND DISPLAY DEVICE HITACHI CHEMICAL COMPANY, LTD. (JP) 2021-07-22 US disclosed
CN-112625004-A Novel photo-activated organic small molecule matrix, preparation method and application thereof in MALDI mass spectrometry detection 苏州大学 2021-04-09 CN disclosed