SCHEMBL131376

SCHEMBL131376

CCN(CC)c1ccc(-c2nnc(-c3ccc(N(CC)CC)cc3)o2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.53
NPC1 O15118 12/20 0.50
RAB9A P51151 12/20 0.50
ALDH1A1 P00352 8/20 0.50
SMN1; SMN2 Q16637 8/20 0.50
KDM4E B2RXH2 6/20 0.50
KMT2A Q03164 6/20 0.50
HPGD P15428 5/20 0.50
MEN1 O00255 5/20 0.50
MAPT P10636 4/20 0.50
HTT P42858 3/20 0.50
LMNA P02545 2/20 0.50
HSD17B10 Q99714 2/20 0.50
USP2 O75604 1/20 0.50
CYP3A4 P08684 2/20 0.47
PSMD14 O00487 1/20 0.47
TSHR P16473 1/20 0.47
MAPK1 P28482 1/20 0.47
RECQL P46063 1/20 0.47
GFER P55789 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10402333 0.93 NPC1 (0.59) APPNPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL169499 0.93 APP (0.65) APPNPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL8925548 0.90 MAPT (0.50) APPNPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL8925543 0.90 MAPT (0.50) APPNPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL12313134 0.90 NPC1 (0.53) APPNPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL14112951 0.88 APP (0.42) APPNPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL12171574 0.86 NPC1 (0.62) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL10806984 0.86 APP (0.56) APPNPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL8179194 0.85 SMN1; SMN2 (0.58) APPNPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL12826704 0.84 NPC1 (0.56) APPNPC1RAB9AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1719 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116377727-A Laser stealth coating for fabric and application method thereof 西京学院 2023-07-04 CN claimed
US-7960080-B2 Oxadiazole containing photoconductors XEROX CORPORATION (US) 2011-06-14 US claimed
US-20090246664-A1 OXADIAZOLE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-10-01 US claimed
US-7291429-B2 Naphthalenetetracarboxylic acid diimide derivatives and electrophotographic photoconductive material using the derivatives SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-11-06 US claimed
US-20050112482-A1 Naphthalenetetracarboxylic acid diimide derivatives and electrophotographic photoconductive material using the derivatives SAMSUNG ELECTRONICS CO., LTD. (KR) 2005-05-26 US claimed
US-6645686-B1 Electrophotographic imaging members XEROX CORPORATION 2003-11-11 US claimed
EP-1011033-A2 Carrier, toner and electrophotographic photoreceptor comprising a carbosiloxane dendrimer-functional vinyl type polymer Dow Corning Toray Silicone Company, Ltd. (JP) 2000-06-21 EP claimed
US-6027840-A Solution for making photoconductive layers in CRTS ORION ELECTRIC CO., LTD. (KR) 2000-02-22 US claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
EP-0050464-B1 PHOTOSENSITIVE MATERIAL FOR ELECTROPHOTOGRAPHY FUJITSU LIMITED (JP) 1985-02-06 EP claimed
US-4471040-A Electrophotographic disazo photosensitive member CANON KABUSHIKI KAISHA (JP) 1984-09-11 US claimed
US-4436801-A Electrophotographic recording element having an aniline sulphonephthelein charge generator ING. C. OLIVETTI & C., S.P.A. (IT) 1984-03-13 US claimed
US-4396695-A MULTILAYER BASF AKTIENGESELLSCHAFT (DE) 1983-08-02 US claimed
EP-0082711-A2 Electrophotographic recording element Ing. C. Olivetti & C., S.p.A. (IT) 1983-06-29 EP claimed
US-4390611-A Electrophotographic photosensitive azo pigment containing members CANON KABUSHIKI KAISHA (JP) 1983-06-28 US claimed
US-4362801-A 2,5-BIS(4'-DIETHYLAMINOPHENYL)-1,3,4-OXADIAZOLE FUJITSU LIMITED (JP) 1982-12-07 US claimed
EP-0050464-A2 Photosensitive material for electrophotography FUJITSU LIMITED (JP) 1982-04-28 EP claimed
US-4063948-A Material for electrophotographic reproduction HOECHST AKTIENGESELLSCHAFT (DT) 1977-12-20 US claimed
US-4026704-A BISAZO DYESTUFF HOECHST AKTIENGESELLSCHAFT (DT) 1977-05-31 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050112482-A1 Naphthalenetetracarboxylic acid diimide derivatives and electrophotographic photoconductive material using the derivatives ADSL, DCLK1, DCLK2 APP 3119/4885NPC1 1586/4885RAB9A 2470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.