SCHEMBL131380

SCHEMBL131380

CC(=O)Oc1[c]cccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.41
HSD17B10 Q99714 4/20 0.41
ALDH1A1 P00352 3/20 0.41
HPGD P15428 2/20 0.41
ELANE P08246 1/20 0.41
ESR1 P03372 1/20 0.41
ITGB3 P05106 1/20 0.41
ITGA2B P08514 1/20 0.41
HMGB1 P09429 1/20 0.41
TSHR P16473 1/20 0.41
GGT1 P19440 1/20 0.41
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41
BLM P54132 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
BACE1 P56817 1/20 0.41
HTT P42858 2/20 0.40
GAA P10253 2/20 0.40
MAPT P10636 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2237469 0.81 ELANE (0.46) KDM4EHSD17B10ALDH1A1HPGDELANE
SCHEMBL7261346 0.81 L3MBTL1 (0.35) HSD17B10ALDH1A1HPGDTSHRNAPRT
SCHEMBL11783113 0.80
SCHEMBL3453964 0.80 HSD17B10 (0.44) KDM4EHSD17B10HPGDTSHRLMNA
SCHEMBL7474694 0.79
SCHEMBL1416065 0.79 MEN1 (0.42) KDM4EHSD17B10ALDH1A1HPGDTSHR
SCHEMBL1416517 0.79 ALDH1A1 (0.45) HSD17B10ALDH1A1PTGS1GAAMAPK1
SCHEMBL2291003 0.79 ELANE (0.45) KDM4EALDH1A1ELANEESR1TSHR
SCHEMBL751033 0.79 RAB9A (0.48) ALDH1A1TSHRMAPK1LMNA
SCHEMBL7723112 0.79 ELANE (0.47) ELANEMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2083 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118281333-A Electrolyte additive, nonaqueous electrolyte and application thereof 深圳市研一新材料有限责任公司 2024-07-02 CN claimed
CN-118281320-A Lithium ion battery electrolyte matched with high-nickel ternary cathode material-silicon-based anode material and lithium ion battery 深圳市研一新材料有限责任公司 2024-07-02 CN claimed
CN-118281321-A Lithium ion battery electrolyte matched with high-nickel ternary cathode material and lithium ion battery 深圳市研一新材料有限责任公司 2024-07-02 CN claimed
CN-118026938-A Pyrazolone ester compound and electrochemical synthesis method thereof 江西本草天工科技有限责任公司 2024-05-14 CN claimed
WO-2024093412-A1 HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 广东中科药物研究有限公司 2024-05-10 WO claimed
CN-115991698-B Heterocyclic compound and preparation method and application thereof 广东中科药物研究有限公司 2024-03-29 CN claimed
US-20230303503-A1 CELL ACTIVATABLE IRON CHELATORS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-09-28 US claimed
CN-116178197-A (Z) -N-substituted enaminone derivative, preparation method and application thereof 浙江医药股份有限公司新昌制药厂 2023-05-30 CN claimed
CN-115991698-A Heterocyclic compound and preparation method and application thereof 广东中科药物研究有限公司 2023-04-21 CN claimed
CN-113754601-B Synthesis method of N2-beta-sulfanyl triazole derivative 周口师范学院 2023-04-11 CN claimed
EP-0019955-A1 Benzofurancarboxylic acid derivatives, their preparation and their inclusion in lipogenesis inhibiting compositions SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1980-12-10 EP claimed
US-4233216-A INTERMEDIATES FOR OXADETHIACEPHALOSPORINS SHIONOGI & CO., LTD. (JP) 1980-11-11 US claimed
US-4226864-A BACTERICIDES, ANTIBIOTICS SHIONOGI & CO., LTD. (JP) 1980-10-07 US claimed
US-4213999-A Inhibition of lipogenesis SHELL OIL COMPANY (US) 1980-07-22 US claimed
US-4198519-A Anti-inflammatory compounds BEECHAM GROUP LIMITED (GB) 1980-04-15 US claimed
US-4193917-A LACTAM COMPOUND USED AS INTERMEDIATE GLAXO LABORATORIES, LIMITED (GB) 1980-03-18 US claimed
US-4153718-A Anti-inflammatory compounds BEECHAM GROUP LIMITED (GB) 1979-05-08 US claimed
US-4006163-A POLYESTERS CIBA-GEIGY CORPORATION (US) 1977-02-01 US claimed
US-3953464-A ANALGESICS, ANTIINFLAMMATORY AGENTS WARNER-LAMBERT COMPANY (US) 1976-04-27 US claimed
US-3953449-A ANALGESICS SYNTHELABO (FR) 1976-04-27 US claimed