Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21282546 | 0.83 | CCKBR (0.39) | CCKBRHRH2OPRM1HTR2BBCHE | |
| SCHEMBL20505796 | 0.81 | CCKBR (0.38) | CCKBRHRH2OPRM1HTR2BBCHE | |
| SCHEMBL23758472 | 0.79 | CCKBR (0.37) | CCKBRHRH2OPRM1HTR2BBCHE | |
| SCHEMBL24202026 | 0.77 | CCKBR (0.38) | CCKBRHRH2OPRM1HTR2BBCHE | |
| SCHEMBL16684897 | 0.77 | CCKBR (0.39) | CCKBRHRH2OPRM1HTR2BBCHE | |
| SCHEMBL1118519 | 0.74 | CCKBR (0.42) | CCKBRHRH2OPRM1HTR2BBCHE | |
| SCHEMBL12013752 | 0.74 | CCKBR (0.42) | CCKBRHRH2OPRM1HTR2BBCHE | |
| SCHEMBL12141050 | 0.74 | CCKBR (0.42) | CCKBRHRH2OPRM1HTR2BBCHE | |
| SCHEMBL1488694 | 0.74 | HTR2A (0.46) | CCKBRLMNACYP2D6HTR2BBCHE | |
| Dimethylamine SCHEMBL8649623 | 0.74 | BCHE (0.39) | CCKBRBCHEHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010113834-A1 | PYRIMIDINE COMPOUND | アステラス製薬株式会社 (JP) | 2010-10-07 | — | — | WO | disclosed |