Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 2/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21282546 | 0.82 | CCKBR (0.39) | CCKBRHRH2OPRM1HTR2BBCHE | |
| SCHEMBL20505796 | 0.80 | CCKBR (0.38) | CCKBRHRH2OPRM1HTR2BBCHE | |
| SCHEMBL23758472 | 0.78 | CCKBR (0.37) | CCKBRHRH2OPRM1HTR2BBCHE | |
| SCHEMBL13142140 | 0.77 | CCKBR (0.36) | CCKBRHRH2OPRM1HTR2BBCHE | |
| SCHEMBL16684897 | 0.76 | CCKBR (0.39) | CCKBRHRH2OPRM1HTR2BBCHE | |
| SCHEMBL24201551 | 0.76 | CCKBR (0.42) | CCKBRHRH2OPRM1HTR2BBCHE | |
| SCHEMBL12141050 | 0.73 | CCKBR (0.42) | CCKBRHRH2OPRM1HTR2BBCHE | |
| SCHEMBL1118519 | 0.73 | CCKBR (0.42) | CCKBRHRH2OPRM1HTR2BBCHE | |
| SCHEMBL12013752 | 0.73 | CCKBR (0.42) | CCKBRHRH2OPRM1HTR2BBCHE | |
| SCHEMBL10819639 | 0.73 | ALDH1A1 (0.39) | CCKBRHRH2OPRM1HTR2BEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939981-A1 | FUSED THIAZOLOPYRIMIDINE DERIVATIVES AS MNKS INHIBITORS | LifeArc (GB) | 2022-01-19 | — | — | EP | disclosed |