Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | PMM2 | O15305 | 2/20 | 0.30 |
| ▸ | MPI | P34949 | 2/20 | 0.30 |
| ▸ | PHOSPHO1 | Q8TCT1 | 2/20 | 0.30 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30687231 | 0.94 | KMT2A (0.35) | PGRMAPTLMNANPSR1CYP1A2 | |
| SCHEMBL13231557 | 0.94 | KMT2A (0.35) | PGRMAPTLMNANPSR1CYP1A2 | |
| SCHEMBL19160269 | 0.92 | PGR (0.32) | PGRMAPTLMNA | |
| SCHEMBL12117277 | 0.92 | CYP1A2 (0.33) | PGRLMNANPSR1CYP1A2CYP2D6 | |
| SCHEMBL19721603 | 0.90 | GPR3 (0.40) | MAPTLMNANPSR1CYP1A2CYP2D6 | |
| SCHEMBL18267483 | 0.86 | KDM4E (0.40) | PGRMAPTLMNANPSR1KMT2A | |
| SCHEMBL17171647 | 0.85 | CYP1A2 (0.30) | CYP1A2CYP2D6KMT2A | |
| SCHEMBL13557575 | 0.83 | GPR3 (0.34) | MAPTALDH1A1HPGDPOLBRAB9A | |
| SCHEMBL18267511 | 0.83 | MAPT (0.47) | PGRMAPTLMNANPSR1CYP1A2 | |
| SCHEMBL19721608 | 0.82 | HTR2A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8384068-B2 | Use of acridine derivatives as matrix materials and/or electron blockers in OLEDs | BASF SE (DE) | 2013-02-26 | — | — | US | disclosed |
| US-20100219406-A1 | USE OF ACRIDINE DERIVATIVES AS MATRIX MATERIALS AND/OR ELECTRON BLOCKERS IN OLEDS | BASF SE (DE) | 2010-09-02 | — | — | US | disclosed |