Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | ITGAL | P20701 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 7/20 | 0.31 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13231557 | 1.00 | KMT2A (0.35) | KMT2ACYP1A2CYP2D6NPSR1LMNA | |
| SCHEMBL12117277 | 0.97 | CYP1A2 (0.33) | KMT2ACYP1A2CYP2D6NPSR1LMNA | |
| SCHEMBL19721603 | 0.96 | GPR3 (0.40) | KMT2ACYP1A2CYP2D6NPSR1LMNA | |
| SCHEMBL13143078 | 0.94 | PGR (0.36) | KMT2ACYP1A2CYP2D6NPSR1LMNA | |
| SCHEMBL18267483 | 0.91 | KDM4E (0.40) | KMT2ANPSR1LMNAITGB2ICAM1 | |
| SCHEMBL17171647 | 0.91 | CYP1A2 (0.30) | KMT2ACYP1A2CYP2D6 | |
| SCHEMBL13557575 | 0.88 | GPR3 (0.34) | GPR3MAPT | |
| SCHEMBL18267511 | 0.88 | MAPT (0.47) | KMT2ACYP1A2NPSR1LMNAPGR | |
| SCHEMBL19721608 | 0.87 | HTR2A (0.35) | — | |
| SCHEMBL16488249 | 0.87 | GPR3 (0.33) | GPR3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285564-A | Dibenzothiophene sulfone compound, and preparation method and application thereof | 黑龙江大学 | 2023-12-26 | — | — | CN | disclosed |