Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | PRCP | P42785 | 8/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15850406 | 1.00 | HTR2C (0.43) | HTR2CPRCPMAPK13MAPK12MAPK11 | |
| SCHEMBL855900 | 0.86 | HTR2C (0.40) | HTR2CPRCPMAPK13MAPK12MAPK11 | |
| SCHEMBL825064 | 0.86 | HTR2C (0.40) | HTR2CPRCPMAPK13MAPK12MAPK11 | |
| SCHEMBL13145270 | 0.85 | DGAT1 (0.42) | HTR2CPRCPOPRM1OPRD1 | |
| SCHEMBL14929968 | 0.83 | HPGDS (0.43) | PRCPMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL10236927 | 0.83 | HPGDS (0.43) | PRCPMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL853975 | 0.82 | HPGDS (0.43) | HTR2CPRCPHPGDS | |
| SCHEMBL13145752 | 0.82 | HPGDS (0.43) | HTR2CPRCPHPGDS | |
| SCHEMBL12175178 | 0.81 | PRCP (0.43) | PRCPMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL12175265 | 0.80 | CFD (0.41) | PRCPMAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010117977-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-10-14 | — | — | WO | disclosed |