Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20669647 | 0.86 | ALDH1A1 (0.53) | CYP2A6CYP1A2ALDH1A1LMNAKDM4E | |
| SCHEMBL706356 | 0.78 | L3MBTL1 (0.57) | CYP2A6CYP1A2ALDH1A1KDM4EGAA | |
| SCHEMBL13180139 | 0.76 | CYP1A2 (0.44) | CYP2A6CYP1A2ALDH1A1LMNAKDM4E | |
| SCHEMBL13146023 | 0.76 | CYP1A2 (0.44) | CYP2A6CYP1A2ALDH1A1LMNAKDM4E | |
| SCHEMBL9478552 | 0.75 | PON1 (0.36) | CYP1A2ALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL13146011 | 0.74 | MAPT (0.54) | CYP2A6CYP1A2ALDH1A1LMNAKDM4E | |
| SCHEMBL11436049 | 0.73 | CYP1A2 (0.42) | CYP2A6CYP1A2ALDH1A1LMNAKDM4E | |
| SCHEMBL599276 | 0.72 | CYP1A2 (0.65) | CYP2A6CYP1A2ALDH1A1LMNAKDM4E | |
| SCHEMBL9164079 | 0.72 | L3MBTL1 (0.35) | CYP1A2L3MBTL1TSHRACHE | |
| SCHEMBL31633434 | 0.72 | L3MBTL1 (0.35) | CYP1A2L3MBTL1TSHRACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200131144-A1 | AMINE OR (THIO)AMIDE CONTAINING LXR MODULATORS | PHENEX-FXR GMBH (DE) | 2020-04-30 | — | — | US | disclosed |
| WO-2019016269-A1 | AMINE OR (THIO)AMIDE CONTAINING LXR MODULATORS | PHENEX-FXR GMBH (DE) | 2019-01-24 | — | — | WO | disclosed |
| US-7794854-B2 | Corannulene compound and organic light-emitting device | CANON KABUSHIKI KAISHA (JP) | 2010-09-14 | — | — | US | disclosed |
| US-7794854-B2 | Corannulene compound and organic light-emitting device | CANON KABUSHIKI KAISHA (JP) | 2010-09-14 | — | — | US | disclosed |
| US-20070049779-A1 | CORANNULENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE | CANON KABUSHIKI KAISHA (JP) | 2007-03-01 | — | — | US | disclosed |
| US-20070049779-A1 | CORANNULENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE | CANON KABUSHIKI KAISHA (JP) | 2007-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131144-A1 | AMINE OR (THIO)AMIDE CONTAINING LXR MODULATORS | NR1H2, NR1H3, NR1H4 | CYP2A6 524/4885CYP1A2 292/4885ALDH1A1 2016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.