SCHEMBL706356

SCHEMBL706356

Cc1ccc2ccccc2c1CCl

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.57
TSHR P16473 6/20 0.54
CYP1A2 P05177 4/20 0.54
CYP2A6 P11509 3/20 0.54
ALDH1A1 P00352 5/20 0.46
HSD17B10 Q99714 5/20 0.44
TDP1 Q9NUW8 3/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
KMT2A Q03164 1/20 0.43
HPGD P15428 3/20 0.42
CYP3A4 P08684 2/20 0.42
KDM4E B2RXH2 2/20 0.42
MAPT P10636 2/20 0.42
GAA P10253 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
NPBWR1 P48145 1/20 0.41
HPRT1 P00492 1/20 0.41
MAPK1 P28482 1/20 0.39
CASP1 P29466 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6190451 0.87 L3MBTL1 (0.44) L3MBTL1TSHRCYP1A2CYP2A6ALDH1A1
SCHEMBL7955051 0.86 TSHR (0.52) L3MBTL1TSHRCYP1A2CYP2A6ALDH1A1
SCHEMBL16042478 0.83 TSHR (0.58) L3MBTL1TSHRCYP1A2CYP2A6ALDH1A1
SCHEMBL6249203 0.83 TSHR (0.58) L3MBTL1TSHRCYP1A2CYP2A6ALDH1A1
SCHEMBL29489290 0.81 TSHR (0.56) L3MBTL1TSHRCYP1A2CYP2A6ALDH1A1
SCHEMBL607362 0.81 CYP1A2 (0.56) L3MBTL1TSHRCYP1A2CYP2A6ALDH1A1
Potassium SCHEMBL29978462 0.81 TSHR (0.56) L3MBTL1TSHRCYP1A2CYP2A6ALDH1A1
SCHEMBL29489289 0.81 TSHR (0.56) L3MBTL1TSHRCYP1A2CYP2A6ALDH1A1
SCHEMBL1538534 0.79 TSHR (0.54) L3MBTL1TSHRCYP1A2CYP2A6ALDH1A1
SCHEMBL821213 0.79 TSHR (0.54) L3MBTL1TSHRCYP1A2CYP2A6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103626621-B 1,2-dihydro cyclobutane is [α] naphthalene new synthetic method also CHEMTARGET TECHNOLOGIES CO., LTD. (CN) 2016-05-04 CN claimed
CN-103626621-A Novel synthetic method of 1,2-dihydro cyclobutene [alpha] naphthalene CHEMTARGET TECHNOLOGIES CO LTD 2014-03-12 CN claimed
US-11685702-B2 Method for producing arene compounds and arene compounds produced by the same JSI SILICONE CO. (KR) 2023-06-27 US disclosed
CN-114574866-A Metal corrosion inhibitor compound and preparation method thereof, corrosion inhibitor composition and application thereof 中国石油天然气股份有限公司 2022-06-03 CN disclosed
CN-107406339-B Method and apparatus for producing alpha-olefin oligomer 三菱化学株式会社 2021-10-26 CN disclosed
US-20210188739-A1 METHOD FOR PRODUCING ARENE COMPOUNDS AND ARENE COMPOUNDS PRODUCED BY THE SAME JSI SILICONE CO. (KR) 2021-06-24 US disclosed
CN-107074679-B Method and apparatus for producing alpha-olefin oligomer 三菱化学株式会社 2020-11-17 CN disclosed
EP-3071562-B1 TETRAHYDRO-BENZODIAZEPINONES HOFFMANN LA ROCHE (CH) 2020-10-14 EP disclosed
CN-107406345-B Process for producing alpha-olefin oligomer 三菱化学株式会社 2020-08-11 CN disclosed
CN-107428629-B α -Process for producing olefin oligomer 三菱化学株式会社 2020-07-28 CN disclosed
US-20200131144-A1 AMINE OR (THIO)AMIDE CONTAINING LXR MODULATORS PHENEX-FXR GMBH (DE) 2020-04-30 US disclosed
EP-0210136-A2 Curable polyether resins CIBA-GEIGY AG (CH) 1987-01-28 EP disclosed
US-4581297-A STEEL BELTED RADIAL TIRES MONSANTO EUROPE, S.A. (BE) 1986-04-08 US disclosed
EP-0150168-A2 Use of metal salts of thiosulphuric -S-esters as rubber/metal bonding promoters MONSANTO EUROPE S.A./N.V. (BE) 1985-07-31 EP disclosed
US-4528195-A Imidazole derivatives and salts thereof, their synthesis and intermediates and pharmaceutical formulations THOROGOOD PETER B (GB) 1985-07-09 US disclosed
EP-0003560-B1 IMIDAZOLE DERIVATIVES AND SALTS THEREOF, THEIR SYNTHESIS, AND PHARMACEUTICAL FORMULATIONS THE WELLCOME FOUNDATION LIMITED (GB) 1984-05-02 EP disclosed
US-4416895-A ANTICOAGULANTS, ANTISHOCK AGENTS BURROUGHS WELLCOME CO. (US) 1983-11-22 US disclosed
EP-0003560-A2 Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations THE WELLCOME FOUNDATION LIMITED (GB) 1979-08-22 EP disclosed
US-4107329-A Fluorinated compounds as therapeutics IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1978-08-15 US disclosed
US-3989746-A ANALGESICS, ANTIINFLAMMATORY AGENTS IKEDA MOHANDO CO., LTD. (JA) 1976-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210188739-A1 METHOD FOR PRODUCING ARENE COMPOUNDS AND ARENE COMPOUNDS PRODUCED BY THE SAME PFAS, FRK, AGPAT2 L3MBTL1 4367/4885TSHR 2847/4885CYP1A2 303/4885
US-20200131144-A1 AMINE OR (THIO)AMIDE CONTAINING LXR MODULATORS NR1H2, NR1H3, NR1H4 L3MBTL1 2981/4885TSHR 86/4885CYP1A2 292/4885
US-11685702-B2 Method for producing arene compounds and arene compounds produced by the same PFAS, FRK, AGPAT2 L3MBTL1 4367/4885TSHR 2847/4885CYP1A2 303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.