Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10150894 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MAPTMAPK1MTOR | |
| SCHEMBL27173452 | 0.81 | ALDH1A1 (0.49) | ALDH1A1MAPTRIPK1CTSSCTSK | |
| SCHEMBL8907649 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPTMAPK1CTSSCTSK | |
| SCHEMBL304497 | 0.77 | FPR2 (0.47) | ALDH1A1MAPTMAPK1ATMMTOR | |
| SCHEMBL634437 | 0.77 | FPR2 (0.47) | ALDH1A1MAPTMAPK1ATMMTOR | |
| SCHEMBL16509205 | 0.76 | TACR3 (0.44) | ALDH1A1MAPTMAPK1ATMMTOR | |
| SCHEMBL890232 | 0.76 | TACR3 (0.44) | ALDH1A1MAPTMAPK1ATMMTOR | |
| SCHEMBL305715 | 0.74 | CTSS (0.47) | ALDH1A1MAPTMAPK1CTSSCTSK | |
| SCHEMBL305716 | 0.74 | CTSS (0.47) | ALDH1A1MAPTMAPK1CTSSCTSK | |
| SCHEMBL8912182 | 0.73 | MTOR (0.44) | ALDH1A1MAPTMAPK1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417126-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2014-07-02 | — | — | EP | disclosed |
| WO-2010117977-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-10-14 | — | — | WO | disclosed |