Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 10/20 | 0.46 |
| ▸ | DRD2 | P14416 | 6/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18601776 | 0.81 | HTR7 (0.53) | SLC6A4DRD4DRD2GSK3BLMNA | |
| SCHEMBL6814945 | 0.81 | HTR7 (0.53) | SLC6A4DRD4DRD2GSK3BLMNA | |
| SCHEMBL6811236 | 0.80 | TRPA1 (0.49) | SLC6A4DRD4DRD2GSK3BLMNA | |
| SCHEMBL318549 | 0.80 | SLC6A4 (0.51) | SLC6A4DRD4DRD2GSK3BLMNA | |
| SCHEMBL10248696 | 0.80 | SLC6A4 (0.51) | SLC6A4DRD4DRD2GSK3BLMNA | |
| SCHEMBL318891 | 0.80 | SLC6A4 (0.51) | SLC6A4DRD4DRD2GSK3BLMNA | |
| SCHEMBL10252245 | 0.80 | SLC6A4 (0.51) | SLC6A4DRD4DRD2GSK3BLMNA | |
| SCHEMBL4467283 | 0.79 | GSK3B (0.71) | SLC6A4DRD4DRD2GSK3BLMNA | |
| SCHEMBL4467279 | 0.79 | GSK3B (0.71) | SLC6A4DRD4DRD2GSK3BLMNA | |
| SCHEMBL4807901 | 0.75 | PPARG (0.44) | SLC6A4DRD4DRD2GSK3BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010113182-A1 | INTERMEDIATES IN THE PREPARATION OF 1,4-DIPHENYL AZETIDINONE | LUPIN LIMITED (IN) | 2010-10-07 | — | — | WO | disclosed |