Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL577901 | 0.88 | ALOX15 (0.40) | RAB9AMEN1KMT2AMITFALOX15 | |
| SCHEMBL586183 | 0.81 | ALOX15 (0.39) | RAB9AMEN1KMT2AMITFALOX15 | |
| SCHEMBL13147683 | 0.79 | ADORA2A (0.42) | MEN1KMT2AKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL577881 | 0.78 | MAPT (0.35) | RAB9AMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL13147752 | 0.77 | CYP19A1 (0.48) | RAB9AMEN1KMT2AALOX15TSHR | |
| SCHEMBL13147740 | 0.77 | IDH1 (0.41) | KMT2AKDM4EHSD17B10ALDH1A1ADORA2A | |
| SCHEMBL13147660 | 0.73 | IDH1 (0.39) | RAB9AKMT2AKDM4EHSD17B10NPC1 | |
| SCHEMBL13147656 | 0.73 | KDM4E (0.47) | RAB9AMEN1KMT2ATSHRKDM4E | |
| SCHEMBL13147742 | 0.72 | IDH1 (0.37) | KDM4EHSD17B10ADORA2AADORA1IDH1 | |
| SCHEMBL13147657 | 0.72 | IDH1 (0.41) | RAB9ACYP1A2ADORA2AADORA1IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118078-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS | IDENIX PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |