Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | GAA | P10253 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | CCR6 | P51684 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3087034 | 0.80 | MAPT (1.00) | CSF1RMAPTGAAKMT2ASMN1; SMN2 | |
| SCHEMBL13148139 | 0.79 | CSF1R (0.66) | CSF1RMAPTGAAKMT2ASMN1; SMN2 | |
| SCHEMBL13148058 | 0.77 | MAPT (0.68) | CSF1RMAPTGAAKMT2ASMN1; SMN2 | |
| Nitrobenzene SCHEMBL28169097 | 0.76 | GAA (0.67) | CSF1RMAPTGAAKMT2ASMN1; SMN2 | |
| SCHEMBL13148083 | 0.76 | CSF1R (0.61) | CSF1RMAPTGAAKMT2ASMN1; SMN2 | |
| SCHEMBL3978132 | 0.75 | ALDH1A1 (0.78) | CSF1RMAPTGAAKMT2ASMN1; SMN2 | |
| SCHEMBL12582512 | 0.74 | GAA (0.62) | CSF1RMAPTGAAKMT2ASMN1; SMN2 | |
| SCHEMBL5049551 | 0.74 | ALOX5 (0.60) | CSF1RMAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL14078174 | 0.73 | CSF1R (0.58) | CSF1RMAPTKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL13148038 | 0.73 | CSF1R (1.00) | CSF1RGAAKMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790724-B2 | c-fms kinase inhibitors | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-09-07 | — | — | US | disclosed |
| US-7790724-B2 | c-fms kinase inhibitors | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-09-07 | — | — | US | disclosed |
| US-7429603-B2 | Such as 5-nitro-furan-2-carboxylic acid (2-piperidin-1-yl-phenyl)-amide; diabetes, angiogenesis, psoriasis, restenosis, schizophrenia, rheumatoid arthritis, cardiovascular disease, cancer | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2008-09-30 | — | — | US | disclosed |
| US-7429603-B2 | Such as 5-nitro-furan-2-carboxylic acid (2-piperidin-1-yl-phenyl)-amide; diabetes, angiogenesis, psoriasis, restenosis, schizophrenia, rheumatoid arthritis, cardiovascular disease, cancer | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2008-09-30 | — | — | US | disclosed |