Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | CCR6 | P51684 | 1/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | CSF1R | P07333 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4318899 | 0.87 | KCNQ2 (0.68) | GAAMAPTL3MBTL1ALDH1A1LMNA | |
| SCHEMBL12582512 | 0.82 | GAA (0.62) | GAAMAPTL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30752017 | 0.81 | ALDH1A1 (0.71) | GAAMAPTL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1439589 | 0.81 | ALDH1A1 (0.71) | GAAMAPTL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3087034 | 0.80 | MAPT (1.00) | GAAMAPTL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13148019 | 0.76 | CSF1R (1.00) | GAAMAPTL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3978132 | 0.75 | ALDH1A1 (0.78) | GAAMAPTL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13148058 | 0.75 | MAPT (0.68) | GAAMAPTL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1439619 | 0.75 | GAA (0.63) | GAAMAPTL3MBTL1ALDH1A1LMNA | |
| SCHEMBL4326786 | 0.74 | ALDH1A1 (0.70) | L3MBTL1ALDH1A1SMN1; SMN2HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107011330-A | BRUTON'S TYROSINE KINASE INHIBITORS | 比奥根MA公司 | 2017-08-04 | — | — | CN | disclosed |