Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.49 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.49 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13149180 | 0.76 | PIM1 (0.53) | PDE10AKDM4EGABRPGABRDALDH1A1 | |
| SCHEMBL15173538 | 0.75 | NR4A2 (0.63) | NR4A2KDM4EALDH1A1HPGDCHUK | |
| SCHEMBL13148311 | 0.74 | CHUK (0.50) | PDE10AKDM4EGABRPGABRDALDH1A1 | |
| SCHEMBL3773933 | 0.74 | CHUK (0.50) | PDE10AKDM4EGABRPGABRDALDH1A1 | |
| SCHEMBL23376878 | 0.73 | SLC22A12 (0.47) | KDM4EALDH1A1DHODHLMNAMAPT | |
| SCHEMBL13148102 | 0.71 | PDE10A (0.58) | PDE10AKDM4EGABRPGABRDALDH1A1 | |
| SCHEMBL19988459 | 0.70 | KDM4E (0.44) | NR4A2KDM4EGABRPGABRDALDH1A1 | |
| SCHEMBL1156242 | 0.69 | NR4A2 (0.50) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL31312750 | 0.69 | TUBB4A (0.62) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL21956760 | 0.68 | KDM5A (0.52) | KDM4EALDH1A1HPGDCHUKPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010115901-A1 | PYRROLOPYRIDINE THERAPEUTIC COMPOUNDS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2010-10-14 | — | — | WO | disclosed |