Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | FAAH | O00519 | 1/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | CA7 | P43166 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13149174 | 0.86 | LMNA (0.76) | ALDH1A1KDM4EMAPK1MEN1KMT2A | |
| SCHEMBL9645824 | 0.85 | KDM4E (0.94) | ALDH1A1KDM4EMAPK1PKMMEN1 | |
| SCHEMBL1019998 | 0.85 | KDM4E (0.94) | ALDH1A1KDM4EMAPK1PKMMEN1 | |
| SCHEMBL13149349 | 0.83 | KDM4E (0.78) | ALDH1A1KDM4EMAPK1MEN1KMT2A | |
| SCHEMBL4486386 | 0.83 | KDM4E (0.78) | ALDH1A1KDM4EMAPK1PKMMEN1 | |
| SCHEMBL25041158 | 0.82 | KDM4E (0.76) | ALDH1A1KDM4EMAPK1PKMMEN1 | |
| SCHEMBL4515670 | 0.82 | KDM4E (0.76) | ALDH1A1KDM4EMAPK1PKMMEN1 | |
| SCHEMBL17696082 | 0.82 | KDM4E (0.76) | ALDH1A1KDM4EMAPK1PKMMEN1 | |
| SCHEMBL4516322 | 0.82 | KDM4E (0.76) | ALDH1A1KDM4EMAPK1PKMMEN1 | |
| SCHEMBL7474168 | 0.82 | KDM4E (0.76) | ALDH1A1KDM4EMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130072497-A1 | N- SUBSTITUTED PIPERAZINES | DOW AGROSCIENCES LLC (US) | 2013-03-21 | — | — | US | disclosed |
| US-20130072497-A1 | N- SUBSTITUTED PIPERAZINES | DOW AGROSCIENCES LLC (US) | 2013-03-21 | — | — | US | disclosed |
| US-8338430-B2 | N-substituted piperazines | DOW AGROSCIENCES, LLC. (US) | 2012-12-25 | — | — | US | disclosed |
| US-8338430-B2 | N-substituted piperazines | DOW AGROSCIENCES, LLC. (US) | 2012-12-25 | — | — | US | disclosed |
| US-20100234391-A1 | N-SUBSTITUTED PIPERAZINES | DOW AGROSCIENCES LLC (US) | 2010-09-16 | — | — | US | disclosed |
| US-20100234391-A1 | N-SUBSTITUTED PIPERAZINES | DOW AGROSCIENCES LLC (US) | 2010-09-16 | — | — | US | disclosed |
| US-7754724-B2 | N-substituted piperazines | DOW AGROSCIENCES LLC (US) | 2010-07-13 | — | — | US | disclosed |
| US-7754724-B2 | N-substituted piperazines | DOW AGROSCIENCES LLC (US) | 2010-07-13 | — | — | US | disclosed |
| US-20070004750-A1 | N-substituted piperazines | CORTEVA AGRISCIENCE LLC | 2007-01-04 | — | — | US | disclosed |
| US-20070004750-A1 | N-substituted piperazines | CORTEVA AGRISCIENCE LLC | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004750-A1 | N-substituted piperazines | PRXL2A, CNPY2, CYP4X1 | ALDH1A1 641/4885KDM4E 280/4885MAPK1 2042/4885 |
| US-20100234391-A1 | N-SUBSTITUTED PIPERAZINES | PRXL2A, CNPY2, CYP4X1 | ALDH1A1 641/4885KDM4E 280/4885MAPK1 2042/4885 |
| US-20130072497-A1 | N- SUBSTITUTED PIPERAZINES | PRXL2A, CNPY2, CYP4X1 | ALDH1A1 641/4885KDM4E 280/4885MAPK1 2042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.