Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TYR | P14679 | 2/20 | 0.52 |
| ▸ | GLB1 | P16278 | 1/20 | 0.52 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.52 |
| ▸ | CTRC | Q99895 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 7/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13149673 | 1.00 | ALOX15 (0.68) | ALOX15LMNATYRGLB1CTRB1 | |
| SCHEMBL28912876 | 0.86 | CYP2A6 (0.57) | ALOX15TSHRALDH1A1TDP1CA1 | |
| SCHEMBL237273 | 0.86 | LMNA (0.67) | ALOX15LMNATYRESR1ESR2 | |
| SCHEMBL440244 | 0.86 | CYP2A6 (0.57) | ALOX15TSHRALDH1A1TDP1CA1 | |
| SCHEMBL6118114 | 0.83 | ALOX15 (1.00) | ALOX15LMNATYRGLB1CTRB1 | |
| SCHEMBL17443 | 0.83 | — | — | |
| SCHEMBL3151141 | 0.80 | ESR1 (0.64) | ALOX15LMNATYRGLB1CTRB1 | |
| SCHEMBL3163611 | 0.80 | ESR1 (0.76) | ALOX15LMNATYRGLB1CTRB1 | |
| Potassium SCHEMBL31030244 | 0.80 | — | — | |
| SCHEMBL28681717 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799949-B2 | Tetraphenylmethane skeleton-containing compound | FUJIFILM CORPORATION (JP) | 2010-09-21 | — | — | US | disclosed |
| US-7799949-B2 | Tetraphenylmethane skeleton-containing compound | FUJIFILM CORPORATION (JP) | 2010-09-21 | — | — | US | disclosed |
| US-20090227812-A1 | TETRAPHENYLMETHANE SKELETON-CONTAINING COMPOUND | FUJIFILM CORPORATION (JP) | 2009-09-10 | — | — | US | disclosed |
| US-20090227812-A1 | TETRAPHENYLMETHANE SKELETON-CONTAINING COMPOUND | FUJIFILM CORPORATION (JP) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227812-A1 | TETRAPHENYLMETHANE SKELETON-CONTAINING COMPOUND | PAH, TSNAX, ZFX | ALOX15 4607/4885LMNA 2152/4885TYR 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.