Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.43 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | EIF4E | P06730 | 5/20 | 0.42 |
| ▸ | RHOC | P08134 | 1/20 | 0.42 |
| ▸ | RHOA | P61586 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628055 | 0.88 | LMNA (0.60) | NOTUMLMNASHMT2SHMT1KDM4E | |
| SCHEMBL13150483 | 0.86 | MPL (0.51) | LMNASHMT2KDM4EALDH1A1HPGD | |
| SCHEMBL13148538 | 0.85 | KDM4E (0.45) | LMNASHMT2KDM4EALDH1A1HPGD | |
| SCHEMBL13148647 | 0.82 | KDM4E (0.39) | NOTUMLMNASHMT2SHMT1KDM4E | |
| SCHEMBL13148954 | 0.78 | LMNA (0.47) | LMNASHMT2KDM4EALDH1A1HPGD | |
| SCHEMBL13148659 | 0.78 | RHOC (0.47) | LMNAKDM4EALDH1A1HPGDGAA | |
| SCHEMBL13148438 | 0.78 | EIF4E (0.46) | NOTUMLMNASHMT2SHMT1KDM4E | |
| SCHEMBL13148445 | 0.75 | LMNA (0.43) | LMNASHMT2SHMT1KDM4EALDH1A1 | |
| SCHEMBL629987 | 0.75 | NOTUM (0.53) | NOTUMEIF4ERHOCRHOACASP3 | |
| SCHEMBL13148641 | 0.73 | KDM4E (0.48) | LMNAKDM4EALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010120741-A1 | COMPOSITIONS AND METHODS FOR MODULATING RETINOL BINDING TO RETINOL BINDING PROTEIN 4 (RBP4) | IRM LLC (US) | 2010-10-21 | — | — | WO | disclosed |