SCHEMBL13151971

SCHEMBL13151971

Cc1cc(Nc2nc(Cl)nc(Nc3ccc(/N=N/c4cc(S(=O)(=O)O)ccc4S(=O)(=O)O)c(C)c3)n2)ccc1/N=N/c1cc(S(=O)(=O)O)ccc1S(=O)(=O)O

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ FUT8 Q9BYC5 1/20 0.49
▸ CA12 O43570 7/20 0.46
▸ CA1 P00915 7/20 0.46
▸ CA2 P00918 7/20 0.46
▸ CA9 Q16790 7/20 0.46
▸ CHAT P28329 3/20 0.43
▸ USP2 O75604 1/20 0.43
▸ APEX1 P27695 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.43
▸ HIF1A Q16665 1/20 0.43
▸ ENPP3 O14638 1/20 0.42
▸ ENPP1 P22413 1/20 0.42
▸ CA14 Q9ULX7 2/20 0.41
▸ P2RX3 P56373 1/20 0.41
▸ SNCA P37840 1/20 0.41
▸ ENPP2 Q13822 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13151833 0.90 ALDH1A1 (0.46) FUT8CHATALDH1A1HIF1AP2RX3
SCHEMBL10284775 0.87 FUT8 (0.48) FUT8CA12CA1CA2CA9
SCHEMBL13924366 0.85 CTRB1 (0.46) FUT8CA12CA1CA2CA9
SCHEMBL10284587 0.85 CD40 (0.48) FUT8CA12CA1CA2CA9
SCHEMBL14468813 0.84 CA12 (0.57) FUT8CA12CA1CA2CA9
SCHEMBL14600411 0.83 FUT8 (0.45) FUT8CA12CA1CA2CA9
SCHEMBL13800014 0.82 CA12 (0.40) FUT8CA12CA1CA2CA9
SCHEMBL12559088 0.81 ENPP2 (0.47) FUT8CHATALDH1A1HIF1ASNCA
SCHEMBL13152017 0.81 ENPP2 (0.53) FUT8CA12CA1CA2CA9
SCHEMBL13924369 0.80 HIF1A (0.55) FUT8ALDH1A1HIF1ASNCAENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7799122-B2 Azo compounds FUJIFILM IMAGING COLORANTS LIMITED (GB) 2010-09-21 — — US disclosed
US-7799122-B2 Azo compounds FUJIFILM IMAGING COLORANTS LIMITED (GB) 2010-09-21 — — US disclosed
US-20100151212-A1 Azo compounds FUJIFILM IMAGING COLORANTS LIMITED (GB) 2010-06-17 — — US disclosed
US-20100151212-A1 Azo compounds FUJIFILM IMAGING COLORANTS LIMITED (GB) 2010-06-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100151212-A1 Azo compounds PAH, CYP1A1, RB1 FUT8 3030/4885CA12 915/4885CA1 889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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