Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | RORA | P35398 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | RORB | Q92753 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10251176 | 0.96 | HSD17B10 (0.44) | HSD17B10PKMNAMPTSMN1; SMN2MAPT | |
| SCHEMBL13152321 | 0.94 | MTNR1B (0.47) | HSD17B10PKMNAMPTCNR2KDM4E | |
| SCHEMBL10254338 | 0.93 | PKM (0.44) | HSD17B10PKMNAMPTSMN1; SMN2MAPT | |
| SCHEMBL10097494 | 0.92 | MAPT (0.48) | HSD17B10MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL10097517 | 0.88 | MAPT (0.50) | HSD17B10MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL10252376 | 0.88 | CNR2 (0.41) | HSD17B10PKMSMN1; SMN2CNR2ALDH1A1 | |
| SCHEMBL13153261 | 0.88 | MTNR1B (0.49) | NAMPTSMN1; SMN2MTNR1BKDRDYRK1A | |
| SCHEMBL13151944 | 0.87 | NAMPT (0.46) | HSD17B10NAMPTSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL10095908 | 0.86 | HSD17B10 (0.40) | HSD17B10PKMNAMPTSMN1; SMN2MAPT | |
| SCHEMBL12108935 | 0.86 | MAPT (0.45) | HSD17B10MAPTALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118009-A1 | HCV INHIBITOR AND THERAPEUTIC AGENT COMBINATIONS | PTC THERAPEUTICS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |