Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 6/20 | 0.43 |
| ▸ | SGK1 | O00141 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 3/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HASPIN | Q8TF76 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13152144 | 0.95 | DYRK1A (0.40) | DYRK1ASGK1ARKITPDE5A | |
| SCHEMBL13152575 | 0.93 | DYRK1A (0.43) | DYRK1ASGK1ARKITPDE5A | |
| SCHEMBL13153271 | 0.92 | GRIK2 (0.40) | DYRK1ASGK1ARKITPDE5A | |
| SCHEMBL13152731 | 0.91 | ALOX15 (0.36) | DYRK1ASGK1HASPINKDM4EALDH1A1 | |
| SCHEMBL13152585 | 0.91 | DYRK1A (0.44) | DYRK1ASGK1PDE5ANPC1HASPIN | |
| SCHEMBL10095875 | 0.87 | DYRK1A (0.41) | DYRK1ASGK1ARKITPDE5A | |
| SCHEMBL13152695 | 0.87 | DYRK1A (0.42) | DYRK1ASGK1KITPDE5AKDM4E | |
| SCHEMBL13152583 | 0.87 | DYRK1A (0.44) | DYRK1APDE5ANPC1HASPINKDM4E | |
| SCHEMBL13152062 | 0.85 | DYRK1A (0.43) | DYRK1ASGK1ARPDE5AKDM4E | |
| SCHEMBL13152633 | 0.84 | DYRK1A (0.42) | DYRK1APDE5ANPC1HASPINKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118009-A1 | HCV INHIBITOR AND THERAPEUTIC AGENT COMBINATIONS | PTC THERAPEUTICS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |