Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 1/20 | 0.53 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13154528 | 0.83 | NPSR1 (0.44) | NPSR1ALDH1A1KMT2ACA12CA4 | |
| SCHEMBL13154538 | 0.82 | ALDH1A1 (0.46) | NPSR1ALDH1A1KMT2ACA12CA4 | |
| SCHEMBL2963432 | 0.71 | CYP2C19 (0.56) | NPSR1ALDH1A1GAAPOLBTHRB | |
| SCHEMBL5606654 | 0.70 | KEAP1 (0.52) | PLA2G7KMT2AGAAMEN1L3MBTL1 | |
| SCHEMBL17549763 | 0.69 | MAPK1 (0.63) | ALDH1A1KMT2AGAAPOLBTHRB | |
| SCHEMBL631623 | 0.69 | RBP4 (1.00) | RBP4KMT2AMEN1 | |
| SCHEMBL13154595 | 0.68 | ALDH1A1 (0.48) | ALDH1A1KMT2ACA12CA4CA7 | |
| SCHEMBL6404409 | 0.68 | KDM4E (0.49) | ALDH1A1KMT2AGAAPOLBTHRB | |
| SCHEMBL7217728 | 0.68 | ALDH1A1 (0.52) | NPSR1ALDH1A1KMT2AGAAPOLB | |
| SCHEMBL13159623 | 0.66 | IDO1 (0.44) | ALDH1A1KMT2AGAAPOLBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010119992-A1 | DERIVATIVES OF N-ACYL-N'-PHENYLPIPERAZINE USEFUL (INTER ALIA) FOR THE PROPHYLAXIS OR TREATMENT OF DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-10-21 | — | — | WO | disclosed |