Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | CASP1 | P29466 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13154647 | 0.93 | NPC1 (0.43) | POLBNPC1RAB9APDGFRBPDGFRA | |
| SCHEMBL718762 | 0.81 | NPC1 (0.44) | POLBNPC1RAB9APDGFRBPDGFRA | |
| SCHEMBL13154646 | 0.77 | DRD2 (0.44) | ALDH1A1MEN1KMT2AMAPTDRD2 | |
| SCHEMBL5755884 | 0.77 | ALDH1A1 (0.56) | POLBNPC1ALDH1A1CASP1HTT | |
| SCHEMBL13549027 | 0.76 | ALDH1A1 (0.42) | POLBNPC1RAB9AALDH1A1CASP1 | |
| SCHEMBL13154640 | 0.76 | DRD2 (0.41) | POLBALDH1A1CASP1HTTMEN1 | |
| SCHEMBL13154648 | 0.75 | EGFR (0.39) | ALDH1A1MAPTDRD2DRD4 | |
| Quinoline SCHEMBL28176263 | 0.75 | ALDH1A1 (0.57) | POLBNPC1RAB9AALDH1A1CASP1 | |
| Quinoline SCHEMBL27674344 | 0.75 | ALDH1A1 (0.57) | POLBNPC1RAB9AALDH1A1CASP1 | |
| SCHEMBL21475276 | 0.74 | NPC1 (0.48) | POLBNPC1RAB9APDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11980086-B2 | Use of transition metal carbene complexes in organic light-emitting diodes (OLEDs) | UDC IRELAND LIMITED (IE) | 2024-05-07 | — | — | US | disclosed |
| US-20240074302-A1 | USE OF TRANSITION METAL CARBENE COMPLEXES IN ORGANIC LIGHT-EMITTING DIODES (OLEDS) | UDC IRELAND LTD (IE) | 2024-02-29 | — | — | US | disclosed |
| US-20140309428-A1 | USE OF TRANSITION METAL CARBENE COMPLEXES IN ORGANIC LIGHT-EMITTING DIODES (OLEDS) | BASF SE (DE) | 2014-10-16 | — | — | US | disclosed |
| US-7803948-B2 | Method for the isomerisation of transition metal complexes containing cyclometallated, carbene ligands | BASF AKTIENGESELLSCHAFT (DE) | 2010-09-28 | — | — | US | disclosed |
| US-20080200686-A1 | Method for the Isomerisation of Transition Metal Complexes Containing Cyclometallated, Carbene Ligands | BASF AKTIENGESELLSCHAFT (DE) | 2008-08-21 | — | — | US | disclosed |
| US-20080018221-A1 | Use Of Transition Metal Carbene Complexes In Organic Light-Emitting Diodes (Oleds) | BASF AKTIENGESELLSCHAFT (DE) | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200686-A1 | Method for the Isomerisation of Transition Metal Complexes Containing Cyclometallated, Carbene Ligands | SCO2, CYC1, CHRM1 | POLB 2753/4885NPC1 3298/4885RAB9A 3563/4885 |
| US-11980086-B2 | Use of transition metal carbene complexes in organic light-emitting diodes (OLEDs) | OCIAD2, OCIAD1, ICOSLG | POLB 1026/4885NPC1 1209/4885RAB9A 2403/4885 |
| US-20080018221-A1 | Use Of Transition Metal Carbene Complexes In Organic Light-Emitting Diodes (Oleds) | OCIAD2, OCIAD1, ICOSLG | POLB 1026/4885NPC1 1209/4885RAB9A 2403/4885 |
| US-20240074302-A1 | USE OF TRANSITION METAL CARBENE COMPLEXES IN ORGANIC LIGHT-EMITTING DIODES (OLEDS) | OCIAD2, OCIAD1, ICOSLG | POLB 1026/4885NPC1 1209/4885RAB9A 2403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.