Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.46 |
| ▸ | DRD4 | P21917 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | DRD1 | P21728 | 5/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 4/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | CD44 | P16070 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4496862 | 0.80 | DRD2 (0.56) | DRD2DRD4PDPK1PARP1PARP10 | |
| SCHEMBL6582387 | 0.78 | DRD2 (0.50) | DRD2DRD4HTR2CPARP1PARP10 | |
| SCHEMBL5755884 | 0.75 | ALDH1A1 (0.56) | DRD2DRD4ALOX15HSD17B10HTR2C | |
| SCHEMBL4504545 | 0.74 | DRD2 (0.47) | DRD2DRD4ALOX15HSD17B10ALDH1A1 | |
| Indoline SCHEMBL29360339 | 0.73 | — | — | |
| Indoline SCHEMBL5629 | 0.73 | — | — | |
| SCHEMBL13154685 | 0.72 | ALDH1A1 (0.53) | DRD2DRD4ALOX15HSD17B10HTR2C | |
| Fluorene SCHEMBL28106539 | 0.72 | PDPK1 (0.50) | DRD2DRD4ALOX15HSD17B10HTR2C | |
| Indoline SCHEMBL23295083 | 0.72 | HTR2C (0.50) | DRD2DRD4ALOX15HSD17B10HTR2C | |
| Indoline SCHEMBL6872936 | 0.72 | HTR2C (0.50) | DRD2DRD4ALOX15HSD17B10HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11980086-B2 | Use of transition metal carbene complexes in organic light-emitting diodes (OLEDs) | UDC IRELAND LIMITED (IE) | 2024-05-07 | — | — | US | disclosed |
| US-20240074302-A1 | USE OF TRANSITION METAL CARBENE COMPLEXES IN ORGANIC LIGHT-EMITTING DIODES (OLEDS) | UDC IRELAND LTD (IE) | 2024-02-29 | — | — | US | disclosed |
| US-20140309428-A1 | USE OF TRANSITION METAL CARBENE COMPLEXES IN ORGANIC LIGHT-EMITTING DIODES (OLEDS) | BASF SE (DE) | 2014-10-16 | — | — | US | disclosed |
| US-7803948-B2 | Method for the isomerisation of transition metal complexes containing cyclometallated, carbene ligands | BASF AKTIENGESELLSCHAFT (DE) | 2010-09-28 | — | — | US | disclosed |
| US-20080200686-A1 | Method for the Isomerisation of Transition Metal Complexes Containing Cyclometallated, Carbene Ligands | BASF AKTIENGESELLSCHAFT (DE) | 2008-08-21 | — | — | US | disclosed |
| US-20080018221-A1 | Use Of Transition Metal Carbene Complexes In Organic Light-Emitting Diodes (Oleds) | BASF AKTIENGESELLSCHAFT (DE) | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200686-A1 | Method for the Isomerisation of Transition Metal Complexes Containing Cyclometallated, Carbene Ligands | SCO2, CYC1, CHRM1 | DRD2 1488/4885DRD4 996/4885ALOX15 769/4885 |
| US-11980086-B2 | Use of transition metal carbene complexes in organic light-emitting diodes (OLEDs) | OCIAD2, OCIAD1, ICOSLG | DRD2 10/4885DRD4 17/4885ALOX15 23/4885 |
| US-20080018221-A1 | Use Of Transition Metal Carbene Complexes In Organic Light-Emitting Diodes (Oleds) | OCIAD2, OCIAD1, ICOSLG | DRD2 10/4885DRD4 17/4885ALOX15 23/4885 |
| US-20240074302-A1 | USE OF TRANSITION METAL CARBENE COMPLEXES IN ORGANIC LIGHT-EMITTING DIODES (OLEDS) | OCIAD2, OCIAD1, ICOSLG | DRD2 10/4885DRD4 17/4885ALOX15 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.