Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 8/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 7/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 6/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4559899 | 0.79 | CHRM2 (0.30) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL31712931 | 0.74 | ADRA2A (0.36) | ADRA2AADRA2CADRA2BADRA1DADRA1A | |
| SCHEMBL7375651 | 0.74 | MAPT (0.52) | KDM4EMAPTLMNACYP1A2CYP3A4 | |
| SCHEMBL13154645 | 0.74 | LMNA (0.52) | ADRA1AKDM4EALDH1A1MAPTLMNA | |
| SCHEMBL30544820 | 0.70 | PRKCI (0.31) | KDM4EMAPT | |
| SCHEMBL28760469 | 0.70 | PRKCI (0.31) | KDM4EMAPT | |
| SCHEMBL13154666 | 0.69 | NOTUM (0.44) | ADRA2AADRA2CADRA2BADRA1DADRA1A | |
| SCHEMBL87693 | 0.68 | MAPT (0.50) | ADRA2AADRA2CADRA2BADRA1DADRA1A | |
| SCHEMBL29463681 | 0.68 | MAPT (0.50) | ADRA2AADRA2CADRA2BADRA1DADRA1A | |
| SCHEMBL30335572 | 0.68 | MAPT (0.50) | ADRA2AADRA2CADRA2BADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11980086-B2 | Use of transition metal carbene complexes in organic light-emitting diodes (OLEDs) | UDC IRELAND LIMITED (IE) | 2024-05-07 | — | — | US | disclosed |
| US-20240074302-A1 | USE OF TRANSITION METAL CARBENE COMPLEXES IN ORGANIC LIGHT-EMITTING DIODES (OLEDS) | UDC IRELAND LTD (IE) | 2024-02-29 | — | — | US | disclosed |
| US-20140309428-A1 | USE OF TRANSITION METAL CARBENE COMPLEXES IN ORGANIC LIGHT-EMITTING DIODES (OLEDS) | BASF SE (DE) | 2014-10-16 | — | — | US | disclosed |
| US-7803948-B2 | Method for the isomerisation of transition metal complexes containing cyclometallated, carbene ligands | BASF AKTIENGESELLSCHAFT (DE) | 2010-09-28 | — | — | US | disclosed |
| US-20080200686-A1 | Method for the Isomerisation of Transition Metal Complexes Containing Cyclometallated, Carbene Ligands | BASF AKTIENGESELLSCHAFT (DE) | 2008-08-21 | — | — | US | disclosed |
| US-20080018221-A1 | Use Of Transition Metal Carbene Complexes In Organic Light-Emitting Diodes (Oleds) | BASF AKTIENGESELLSCHAFT (DE) | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200686-A1 | Method for the Isomerisation of Transition Metal Complexes Containing Cyclometallated, Carbene Ligands | SCO2, CYC1, CHRM1 | ADRA2A 1527/4885ADRA2C 1248/4885ADRA2B 1742/4885 |
| US-11980086-B2 | Use of transition metal carbene complexes in organic light-emitting diodes (OLEDs) | OCIAD2, OCIAD1, ICOSLG | ADRA2A 3751/4885ADRA2C 3926/4885ADRA2B 3182/4885 |
| US-20080018221-A1 | Use Of Transition Metal Carbene Complexes In Organic Light-Emitting Diodes (Oleds) | OCIAD2, OCIAD1, ICOSLG | ADRA2A 3751/4885ADRA2C 3926/4885ADRA2B 3182/4885 |
| US-20240074302-A1 | USE OF TRANSITION METAL CARBENE COMPLEXES IN ORGANIC LIGHT-EMITTING DIODES (OLEDS) | OCIAD2, OCIAD1, ICOSLG | ADRA2A 3751/4885ADRA2C 3926/4885ADRA2B 3182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.